PROKR1
| Gene Symbol | PROKR1 |
|---|---|
| Entrez Gene | 10887 |
| Alt Symbol | GPR73, GPR73a, PKR1, ZAQ |
| Species | Human |
| Gene Type | protein-coding |
| Description | prokineticin receptor 1 |
| Other Description | G protein-coupled receptor 73|G protein-coupled receptor ZAQ|G-protein coupled receptor 73|G-protein coupled receptor ZAQ|PK-R1 |
| Swissprots | Q8NFJ7 A5JUU2 Q53QT9 Q8TCW9 |
| Accessions | AAY24114 EAW99869 Q8TCW9 AB084080 BAC24021 AF506287 AAM48127 AY089976 AAM11892 BC100960 AAI00961 EF577399 ABQ52419 NM_138964 NP_620414 |
| Function | Receptor for prokineticin 1. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. May play a role during early pregnancy. {ECO:0000269|PubMed:18339712}. |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Specificity | Localizes to glandular epithelium, stroma and vascular endothelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non-pregnant endometrium. Expressed in the stomach, throughout the small intestine, colon, rectum, thyroid gland, pituitary gland, salivary gland, adrenal gland, testis, ovary, brain, spleen, prostate and pancreas. {ECO:0000269|PubMed:18339712}. |
PROKR1 overexpression lysate - LY403372 from Acris Antibodies
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Prokineticin R1/PROKR1 Overexpression Lysate (Native) - NBP2-04419 from Novus Biologicals
![Western Blot: PROKR1 Overexpression Lysate (Adult Normal) [NBP2-04419] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PROKR1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8101_PROKR1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-04419-img0001.jpg)
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Panoply™ Human PROKR1 Knockdown Stable Cell Line - CSC-DC012442 from Creative biogene
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