Gene Symbol | PROKR1 |
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Entrez Gene | 10887 |
Alt Symbol | GPR73, GPR73a, PKR1, ZAQ |
Species | Human |
Gene Type | protein-coding |
Description | prokineticin receptor 1 |
Other Description | G protein-coupled receptor 73|G protein-coupled receptor ZAQ|G-protein coupled receptor 73|G-protein coupled receptor ZAQ|PK-R1 |
Swissprots | Q8NFJ7 A5JUU2 Q53QT9 Q8TCW9 |
Accessions | AAY24114 EAW99869 Q8TCW9 AB084080 BAC24021 AF506287 AAM48127 AY089976 AAM11892 BC100960 AAI00961 EF577399 ABQ52419 NM_138964 NP_620414 |
Function | Receptor for prokineticin 1. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. May play a role during early pregnancy. {ECO:0000269|PubMed:18339712}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Localizes to glandular epithelium, stroma and vascular endothelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non-pregnant endometrium. Expressed in the stomach, throughout the small intestine, colon, rectum, thyroid gland, pituitary gland, salivary gland, adrenal gland, testis, ovary, brain, spleen, prostate and pancreas. {ECO:0000269|PubMed:18339712}. |
PROKR1 Antibody Blocking Peptide - LS-E28692 from LifeSpan Bioscience
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PROKR1 Antibody Blocking Peptide - LS-E29168 from LifeSpan Bioscience
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PROKR1 fusion protein - Ag15838 from Proteintech Group
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PROKR1 fusion protein - Ag17187 from Proteintech Group
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Recombinant Human PROKR1, GST-tagged - PROKR1-1974H from Creative Biomart
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Recombinant Prokineticin Receptor 1 (PKR1) - RPA203Hu01 from Uscn Life Science Inc.
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Recombinant Prokineticin Receptor 1 (PKR1) - RPA203Mu01 from Uscn Life Science Inc.
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Recombinant Prokineticin Receptor 1 (PKR1) - RPA203Ra01 from Uscn Life Science Inc.
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Recombinant Prokineticin Receptor 1 (PKR1) - RPA203Bo01 from Uscn Life Science Inc.
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ChemiSCREEN™ Human PK1 Prokineticin Receptor Membrane Preparation - HTS074M from EMD Millipore
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PKR1 (F58) Peptide - BS2957P from Bioworld Technology
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Recombinant Prokineticin Receptor 1 (PKR1) - RPA203Hu01 from Cloud-clone
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GPR73 / Prokineticin receptor 1 - TP319745 from Acris Antibodies
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Prokineticin R1/PROKR1 Recombinant Protein Antigen - NBP1-83337PEP from Novus Biologicals
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GPR73a Blocking Peptide - abx162003 from Abbexa
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PROKR1 Peptide, Human - M34GP12442H from Creative Peptides
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GPR73a Blocking Peptide - CBP4792 from Cohesion Biosciences
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GPR73a peptide - orb315936 from Biorbyt
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Prokineticin receptor 1 (PROKR1), Recombinant Protein - MBS7026993 from MyBioSource
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