Gene Symbol | PROKR1 |
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Entrez Gene | 10887 |
Alt Symbol | GPR73, GPR73a, PKR1, ZAQ |
Species | Human |
Gene Type | protein-coding |
Description | prokineticin receptor 1 |
Other Description | G protein-coupled receptor 73|G protein-coupled receptor ZAQ|G-protein coupled receptor 73|G-protein coupled receptor ZAQ|PK-R1 |
Swissprots | Q8NFJ7 A5JUU2 Q53QT9 Q8TCW9 |
Accessions | AAY24114 EAW99869 Q8TCW9 AB084080 BAC24021 AF506287 AAM48127 AY089976 AAM11892 BC100960 AAI00961 EF577399 ABQ52419 NM_138964 NP_620414 |
Function | Receptor for prokineticin 1. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. May play a role during early pregnancy. {ECO:0000269|PubMed:18339712}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Localizes to glandular epithelium, stroma and vascular endothelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non-pregnant endometrium. Expressed in the stomach, throughout the small intestine, colon, rectum, thyroid gland, pituitary gland, salivary gland, adrenal gland, testis, ovary, brain, spleen, prostate and pancreas. {ECO:0000269|PubMed:18339712}. |
Human-PROKR1-cDNA-Clone - DC09178 from Abgent, a WuXi AppTec company
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Human Prokineticin R1/PROKR1 (NP_620414) VersaClone cDNA - RDC0171 from R&D Systems
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Mouse Prokineticin R1/PROKR1 (NP_067356) VersaClone cDNA - RDC0673 from R&D Systems
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PROKR1 - MBS1269295 from MyBioSource
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Human PROKR1 cDNA clone(NM_138964.2) - CDFG008312 from Creative Biomart
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Human PROKR1 ORF Clone(NM_138964.2) - CDCR317040 from Creative Biomart
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Human PROKR1 ORF Clone(NM_138964.2) - CDCR317041 from Creative Biomart
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Human PROKR1 ORF Clone(NM_138964.2) - CDCR317042 from Creative Biomart
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Human PROKR1 ORF Clone(NM_138964.2) - CDCR317040 from Creative biogene
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Human PROKR1 ORF Clone (BC100960) - CDCS416841 from Creative biogene
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Human PROKR1 cDNA Clone(NM_138964.2) - CDFG008312 from Creative biogene
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