HVCN1

Gene Symbol HVCN1
Entrez Gene 84329
Alt Symbol HV1, VSOP
Species Human
Gene Type protein-coding
Description hydrogen voltage gated channel 1
Other Description hydrogen voltage-gated channel 1|voltage sensor domain-only protein|voltage-gated hydrogen channel 1
Swissprots A8MQ37 Q6UW11 Q96IS5 B4DEB3 Q96D96 F8WCH5
Accessions EAW97933 EAW97934 EAW97935 EAW97936 EAW97937 Q96D96 AK293543 BAG57024 AY359054 AAQ89413 BC007277 AAH07277 BC009731 AAH09731 BC032672 AAH32672 BP369986 BP375483 DB310328 GU211002 ADA61023 JF432642 ADZ15859 XM_005253948 XP_005254005 XM_011538838 XP_011537140 XM_011538839 XP_011537141 XM_011538840 XP_011537142 XM_011538841 XP_011537143 XM_011538842 XP_011537144 XM_011538843 XP_011537145 XM_011538844 XP_011537146 XM_011538845 XP_011537147 XM_011538846 XP_011537148 XM_011538847 XP_011537149 XM_011538848 XP_011537150 NM_001040107 NP_001035196 NM_001256413 NP_001243342 NM_032369 NP_115745
Function Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient. Proton efflux, accompanied by membrane depolarization, facilitates acute production of reactive oxygen species in phagocytosis. {ECO:0000269|PubMed:16554753, ECO:0000269|PubMed:20037153, ECO:0000269|PubMed:22020278}.
Subcellular Location Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Detected mainly at intracellular membranes upon overexpression in HeLa cells (PuMed:20147290), but not in other cell types.
Tissue Specificity Enriched in immune tissues, such as lymph nodes, B-lymphocytes, monocytes and spleen. {ECO:0000269|PubMed:16554753}.

HVCN1 (K-11) - sc-136712 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
HVCN1 (K-11): sc-136712. Western blot analysis of HVCN1 expression in Jurkat whole cell lysate.

HVCN1 (H-113) - sc-292206 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

HVCN1 (S-12) - sc-136714 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-HVCN1 antibody - ab117520 from Abcam

Prices $378.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab117520, at 5 µg/ml, staining HVCN1 in Formalin-fixed, Paraffin-embedded Human spleen tissue by Immunohistochemistry.

Anti-HVCN1 antibody - ab76847 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-HVCN1 / HV1 Antibody (N-Terminus) - LS-C144935 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-HVCN1 / HV1 Antibody (aa1-30, AP) - LS-C236463 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HVCN1 / HV1 Antibody (aa1-30, APC) - LS-C236464 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HVCN1 / HV1 Antibody (aa1-30, Biotin) - LS-C236466 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HVCN1 / HV1 Antibody (aa1-30, FITC) - LS-C236467 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HVCN1 / HV1 Antibody (aa1-30) - LS-C322128 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HVCN1 / HV1 Antibody (aa1-30, PE) - LS-C236470 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HVCN1 / HV1 Antibody (aa1-30, Azide-free, HRP) - LS-C249243 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HVCN1 / HV1 Antibody (C-Terminus) - LS-C146080 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RGD1310788 antibody LS-C146080 Western blot of Rat Muscle lysate. Antibody concentration 1 ug/ml.

Anti-HVCN1 / HV1 Antibody (aa1-30) - LS-C165091 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of HVCN1 Antibody in Jurkat cell line lysates (35 ug/lane). HVCN1 (arrow) was detected using the purified antibody.

Anti-HVCN1 / HV1 Antibody (C-Terminus) IHC-plus™ - LS-B5319 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-HVCN1 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5319 concentration 5 ug/ml.

HVCN1 Antibody - NBP1-76278 from Novus Biologicals

Prices $369.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: HVCN1 Antibody [NBP1-76278] - Rat spleen tissue with HVCN1 antibody at 5 ug/mL.

HVCN1 Antibody - NBP1-06585 from Novus Biologicals

Prices $299.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Western Blot: HVCN1 Antibody [NBP1-06585] - HVCN1 expression in human peripheral blood naive (CD27-) B cells and memory (CD27+) B cells

HVCN1 Antibody - NBP1-81643 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-HVCN1 antibody produced in rabbit - SAB3500536 from Sigma-Aldrich

Prices $347.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-HVCN1: <B>Cat. No. SAB3500536</B>: HVCN1 in human spleen tissue lysate with HVCN1 antibody at (A) 0.5 and (B) 1 μg/mL.

Anti-HVCN1 antibody produced in rabbit - HPA039329 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-HVCN1: <B>Cat. No. HPA039329</B>: Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in subsets of lymphoid cells outside reaction centra.

ANTI-HVCN1(N-TERMINAL) antibody produced in rabbit - SAB1306966 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-HVCN1 (N-term): <B>Cat. No. SAB1306966</B>: Western blot analysis of HVCN1 Antibody (N-term)in Jurkat cell line lysates (35 μg/lane).

Anti-HVCN1 antibody produced in rabbit - SAB2900880 from Sigma-Aldrich

Prices $465.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-HVCN1 (Internal), antibody produced in rabbit: <B>Cat. No. SAB2900880</B>: Anti-HVCN1 antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 μg/mL.

HVCN1 Antibody - N-terminal region (OAAB02457) - OAAB02457 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

HVCN1-Antibody-N-term - AP5042a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of HVCN1 Antibody (N-term)(Cat. #AP5042a) in Jurkat cell line lysates (35ug/lane).HVCN1 (arrow) was detected using the purified Pab.
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