HVCN1

Gene Symbol HVCN1
Entrez Gene 84329
Alt Symbol HV1, VSOP
Species Human
Gene Type protein-coding
Description hydrogen voltage gated channel 1
Other Description hydrogen voltage-gated channel 1|voltage sensor domain-only protein|voltage-gated hydrogen channel 1
Swissprots A8MQ37 Q6UW11 Q96IS5 B4DEB3 Q96D96 F8WCH5
Accessions EAW97933 EAW97934 EAW97935 EAW97936 EAW97937 Q96D96 AK293543 BAG57024 AY359054 AAQ89413 BC007277 AAH07277 BC009731 AAH09731 BC032672 AAH32672 BP369986 BP375483 DB310328 GU211002 ADA61023 JF432642 ADZ15859 XM_005253948 XP_005254005 XM_011538838 XP_011537140 XM_011538839 XP_011537141 XM_011538840 XP_011537142 XM_011538841 XP_011537143 XM_011538842 XP_011537144 XM_011538843 XP_011537145 XM_011538844 XP_011537146 XM_011538845 XP_011537147 XM_011538846 XP_011537148 XM_011538847 XP_011537149 XM_011538848 XP_011537150 NM_001040107 NP_001035196 NM_001256413 NP_001243342 NM_032369 NP_115745
Function Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient. Proton efflux, accompanied by membrane depolarization, facilitates acute production of reactive oxygen species in phagocytosis. {ECO:0000269|PubMed:16554753, ECO:0000269|PubMed:20037153, ECO:0000269|PubMed:22020278}.
Subcellular Location Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Detected mainly at intracellular membranes upon overexpression in HeLa cells (PuMed:20147290), but not in other cell types.
Tissue Specificity Enriched in immune tissues, such as lymph nodes, B-lymphocytes, monocytes and spleen. {ECO:0000269|PubMed:16554753}.

HVCN1 CRISPR/Cas9 KO Plasmid (h) - sc-417832 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HVCN1 HDR Plasmid (h) - sc-417832-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HVCN1 Double Nickase Plasmid (h) - sc-417832-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HVCN1 Double Nickase Plasmid (h2) - sc-417832-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HVCN1 CRISPR Activation Plasmid (h) - sc-417832-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HVCN1 CRISPR Activation Plasmid (h2) - sc-417832-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HVCN1 Lentiviral Activation Particles (h) - sc-417832-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HVCN1 Lentiviral Activation Particles (h2) - sc-417832-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HVCN1 siRNA (h) - sc-96062 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HVCN1 shRNA Plasmid (h) - sc-96062-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HVCN1 shRNA (h) Lentiviral Particles - sc-96062-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU116721 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10409 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10409 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

HVCN1 siRNA (Human) - CRJ3448 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HVCN1 RNAi - H00084329-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

HVCN1 - MBS828361 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human HVCN1 (NM_032369.3) - SHH316141 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human HVCN1(NM_001040107.1) - SHH136685 from Creative biogene

Category siRNA
Species Reactivities Human

HVCN1 shRNA Plasmid (Human) - CHJ3448 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HVCN1 miRNA 3'UTR clone - MiUTR1H-04763 from Creative biogene

Species Reactivities Human

HVCN1 miRNA 3'UTR clone - MiUTR3H-11730 from Creative biogene

Species Reactivities Human
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