HVCN1

Gene Symbol HVCN1
Entrez Gene 84329
Alt Symbol HV1, VSOP
Species Human
Gene Type protein-coding
Description hydrogen voltage gated channel 1
Other Description hydrogen voltage-gated channel 1|voltage sensor domain-only protein|voltage-gated hydrogen channel 1
Swissprots A8MQ37 Q6UW11 Q96IS5 B4DEB3 Q96D96 F8WCH5
Accessions EAW97933 EAW97934 EAW97935 EAW97936 EAW97937 Q96D96 AK293543 BAG57024 AY359054 AAQ89413 BC007277 AAH07277 BC009731 AAH09731 BC032672 AAH32672 BP369986 BP375483 DB310328 GU211002 ADA61023 JF432642 ADZ15859 XM_005253948 XP_005254005 XM_011538838 XP_011537140 XM_011538839 XP_011537141 XM_011538840 XP_011537142 XM_011538841 XP_011537143 XM_011538842 XP_011537144 XM_011538843 XP_011537145 XM_011538844 XP_011537146 XM_011538845 XP_011537147 XM_011538846 XP_011537148 XM_011538847 XP_011537149 XM_011538848 XP_011537150 NM_001040107 NP_001035196 NM_001256413 NP_001243342 NM_032369 NP_115745
Function Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient. Proton efflux, accompanied by membrane depolarization, facilitates acute production of reactive oxygen species in phagocytosis. {ECO:0000269|PubMed:16554753, ECO:0000269|PubMed:20037153, ECO:0000269|PubMed:22020278}.
Subcellular Location Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Detected mainly at intracellular membranes upon overexpression in HeLa cells (PuMed:20147290), but not in other cell types.
Tissue Specificity Enriched in immune tissues, such as lymph nodes, B-lymphocytes, monocytes and spleen. {ECO:0000269|PubMed:16554753}.

HVCN1-Over-expression-Lysate - LY14463a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag HVCN1 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the HVCN1 gene.

HVCN1 overexpression lysate - LY410163 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

HVCN1 overexpression lysate - LY421678 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

HVCN1 Overexpression Lysate (Native) - NBP2-08501 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: HVCN1 Overexpression Lysate (Adult Normal) [NBP2-08501] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for HVCN1.

HVCN1 Overexpression Lysate (Native) - NBP2-06036 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: HVCN1 Overexpression Lysate (Adult Normal) [NBP2-06036] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for HVCN1.

Panoply™ Human HVCN1 Knockdown Stable Cell Line - CSC-DC007363 from Creative biogene

Category Cell Line
Species Human
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