CELF1

Gene Symbol	CELF1
Entrez Gene	10658
Alt Symbol	BRUNOL2, CUG-BP, CUGBP, CUGBP1, EDEN-BP, NAB50, NAPOR, hNab50
Species	Human
Gene Type	protein-coding
Description	CUGBP, Elav-like family member 1
Other Description	50 kDa nuclear polyadenylated RNA-binding protein|CELF-1|CUG RNA-binding protein|CUG triplet repeat RNA-binding protein 1|CUG triplet repeat, RNA binding protein 1|CUG triplet repeat, RNA-binding protein 1|CUG-BP- and ETR-3-like factor 1|CUG-BP1|CUGBP Elav-like family member 1|EDEN-BP homolog|RNA-binding protein BRUNOL-2|bruno-like 2|bruno-like protein 2|deadenylation factor CUG-BP|embryo deadenylation element binding protein|embryo deadenylation element-binding protein homolog|nuclear polyadenylated RNA-binding protein, 50-kD
Swissprots	Q9NR06 D3DQS0 B4E2U5 Q9NP83 Q4LE52 F8W940 Q92879
Accessions	EAW67906 EAW67907 EAW67908 EAW67909 EAW67910 EAW67911 EAW67912 Q92879 AB210019 BAE06101 AF248648 AAF86230 AF267533 AAF78955 AF267534 AAF78956 AJ007988 CAC20566 AK054655 AK056024 AK057016 AK304430 BAG65257 AK307679 BC031079 AAH31079 BC036782 BM737883 CB960956 DA217269 DA320861 DB162286 DQ893717 ABM84643 U63289 AAC50895 XM_011519847 XP_011518149 XM_011519848 XP_011518150 XM_011519849 XP_011518151 XM_011519850 XP_011518152 XM_011519851 XP_011518153 XM_011519852 XP_011518154 XM_011519853 XP_011518155 XM_011519854 XP_011518156 XM_011519855 XP_011518157 XM_011519856 XP_011518158 XM_011519857 XP_011518159 XM_011519858 XP_011518160 XM_011519859 XP_011518161 NM_001025596 NP_001020767 NM_001172639 NP_001166110 NM_001172640 NP_001166111 NM_006560 NP_006551 NM_198700 NP_941989
Function	RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon but exclusion of the non-muscle (NM) exon in actinin pre- mRNAs. Activates SM exon 5 inclusion by antagonizing the repressive effect of PTB. Promotes exclusion of exon 11 of the INSR pre-mRNA. Inhibits, together with HNRNPH1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Increases translation and controls the choice of translation initiation codon of CEBPB mRNA. Increases mRNA translation of CEBPB in aging liver (By similar
Subcellular Location	Nucleus {ECO:0000269|PubMed:8948631}. Cytoplasm {ECO:0000269|PubMed:8948631}. Note=RNA-binding activity is detected in both nuclear and cytoplasmic compartments.
Tissue Specificity	Ubiquitous. {ECO:0000269|PubMed:10893231, ECO:0000269|PubMed:11158314, ECO:0000269|PubMed:16862542}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CUGBP1 293T Cell Transient Overexpression Lysate(Denatured) - H00010658-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

CELF1 overexpression lysate - LY401964 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CELF1 overexpression lysate - LY404819 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

CELF1 overexpression lysate - LY422453 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

CELF1 overexpression lysate - LY433163 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CELF1 overexpression lysate - LY433208 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CELF1 293 Cell Lysate - 401747 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

CELF1 293 Cell Lysate - 403457 from ABBIOTEC Category Cell Lysate Prices $672.00 Sizes 100 µg

CUGBP1/CELF1 Overexpression Lysate (Native) - NBL1-09605 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

CUGBP1/CELF1 Overexpression Lysate (Native) - NBL1-09604 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

CUG-BP1 (h2): 293ST Lysate - sc-159206 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

CELF1 Over-expression Lysate Product - GWB-DA2D90 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

CELF1 Over-expression Lysate Product - GWB-C39466 from Genway Biotech Category Cell Lysate Prices $756.00 Sizes 100 µg Species Human

CUGBP1/CELF1 Overexpression Lysate (Denatured) - H00010658-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

CUGBP1 Overexpression Lysate (Denatured) - H00010658-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Panoply™ Human CELF1 Knockdown Stable Cell Line - CSC-DC002951 from Creative biogene Category Cell Line Species Human

CELF1 KO Cell Lysate-HEK293T - CLKO-0748 from Creative biogene Category Cell Lysate

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