CELF1

Gene Symbol	CELF1
Entrez Gene	10658
Alt Symbol	BRUNOL2, CUG-BP, CUGBP, CUGBP1, EDEN-BP, NAB50, NAPOR, hNab50
Species	Human
Gene Type	protein-coding
Description	CUGBP, Elav-like family member 1
Other Description	50 kDa nuclear polyadenylated RNA-binding protein|CELF-1|CUG RNA-binding protein|CUG triplet repeat RNA-binding protein 1|CUG triplet repeat, RNA binding protein 1|CUG triplet repeat, RNA-binding protein 1|CUG-BP- and ETR-3-like factor 1|CUG-BP1|CUGBP Elav-like family member 1|EDEN-BP homolog|RNA-binding protein BRUNOL-2|bruno-like 2|bruno-like protein 2|deadenylation factor CUG-BP|embryo deadenylation element binding protein|embryo deadenylation element-binding protein homolog|nuclear polyadenylated RNA-binding protein, 50-kD
Swissprots	Q9NR06 D3DQS0 B4E2U5 Q9NP83 Q4LE52 F8W940 Q92879
Accessions	EAW67906 EAW67907 EAW67908 EAW67909 EAW67910 EAW67911 EAW67912 Q92879 AB210019 BAE06101 AF248648 AAF86230 AF267533 AAF78955 AF267534 AAF78956 AJ007988 CAC20566 AK054655 AK056024 AK057016 AK304430 BAG65257 AK307679 BC031079 AAH31079 BC036782 BM737883 CB960956 DA217269 DA320861 DB162286 DQ893717 ABM84643 U63289 AAC50895 XM_011519847 XP_011518149 XM_011519848 XP_011518150 XM_011519849 XP_011518151 XM_011519850 XP_011518152 XM_011519851 XP_011518153 XM_011519852 XP_011518154 XM_011519853 XP_011518155 XM_011519854 XP_011518156 XM_011519855 XP_011518157 XM_011519856 XP_011518158 XM_011519857 XP_011518159 XM_011519858 XP_011518160 XM_011519859 XP_011518161 NM_001025596 NP_001020767 NM_001172639 NP_001166110 NM_001172640 NP_001166111 NM_006560 NP_006551 NM_198700 NP_941989
Function	RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon but exclusion of the non-muscle (NM) exon in actinin pre- mRNAs. Activates SM exon 5 inclusion by antagonizing the repressive effect of PTB. Promotes exclusion of exon 11 of the INSR pre-mRNA. Inhibits, together with HNRNPH1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Increases translation and controls the choice of translation initiation codon of CEBPB mRNA. Increases mRNA translation of CEBPB in aging liver (By similar
Subcellular Location	Nucleus {ECO:0000269|PubMed:8948631}. Cytoplasm {ECO:0000269|PubMed:8948631}. Note=RNA-binding activity is detected in both nuclear and cytoplasmic compartments.
Tissue Specificity	Ubiquitous. {ECO:0000269|PubMed:10893231, ECO:0000269|PubMed:11158314, ECO:0000269|PubMed:16862542}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CUG-BP1 full length protein - ab153111 from Abcam Category Protein Source Wheat germ Species Human

CELF1 / CUGBP1 Antibody Blocking Peptide - LS-E2910 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CELF1 / CUGBP1 Antibody Blocking Peptide - LS-E14693 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CUGBP1/CELF1 Protein - H00010658-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

CUGBP1-Antibody-N-term-Blocking-peptide - BP14036a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CUGBP1 Blocking Peptide - 33R-1032 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CUGBP1 Blocking Peptide - abx063695 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Chicken, Zebrafish

CUGBP1 - H00010658-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CUGBP1 - H00010658-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CUGBP1 fusion protein - Ag14605 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

CUGBP1 fusion protein - ag3677 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human CUGBP1, His-tagged - CUGBP1-11699H from Creative Biomart Category Protein Source E.coli Species Human

CUGBP1 Blocking Peptide - CBP2501 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Chicken, Zebrafish

CUG-BP1/2 (K95) Peptide - BS2339P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human CUGBP Elav-like family member 1(CELF1) - CSB-YP846108HU CSB-EP846108HU CSB-BP846108HU CSB-MP846108HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CELF1 Protein - abx163272 from Abbexa Category Protein Species Human, Mouse

CUGBP1 (transcript variant 1) - TP306275 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

CUGBP1 (transcript variant 2) - TP321943 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

CELF1 Peptide, Human - M34GP02951H from Creative Peptides Category Peptide Source Synthetic. Species Human

CELF1 peptide - orb218364 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Zebrafish, Cat

CUGBP Elav-like family member 1 (CELF1), Recombinant Protein - MBS1348321 from MyBioSource Category Protein Prices $1,270.00, $1,270.00, $1,490.00, $1,490.00, $2,080.00, $2,080.00, $2,545.00, $2,545.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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