LPCAT2

Gene Symbol	LPCAT2
Entrez Gene	54947
Alt Symbol	AYTL1, LysoPAFAT
Species	Human
Gene Type	protein-coding
Description	lysophosphatidylcholine acyltransferase 2
Other Description	1-AGP acyltransferase 11|1-AGPAT 11|1-acylglycerol-3-phosphate O-acyltransferase 11|1-acylglycerophosphocholine O-acyltransferase|1-alkylglycerophosphocholine O-acetyltransferase|LPAAT-alpha|LPC acyltransferase 2|LPCAT-2|acetyl-CoA:lyso-PAF acetyltransferase|acetyl-CoA:lyso-platelet-activating factor acetyltransferase|acyl-CoA:lysophosphatidylcholine acyltransferase 2|acyltransferase like 1|acyltransferase-like 1|lyso-PAF acetyltransferase|lyso-platelet-activating factor (PAF) acetyltransferase|lysoPC acyltransferase 2|lysophosphatidic acid acyltransferase alpha
Swissprots	A3KBM1 Q9NX23 Q6MZJ6 Q7L5N7
Accessions	CCF76984 EAW82829 Q7L5N7 AB244718 BAF47696 AI915099 AK000488 BAA91199 AK023271 AK126523 AK308386 AW366682 BC002472 AAH02472 BC005981 BG772279 BX641069 CAE46034 EU831434 ACE87121 EU831526 ACE86445 HG508117 XM_005256006 XP_005256063 XM_006721211 XP_006721274 XM_011523169 XP_011521471 NM_017839 NP_060309
Function	Possesses both acyltransferase and acetyltransferase activities. Activity is calcium-dependent. Involved in platelet- activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso- PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). Also converts lyso-PAF to 1-O-alkyl-2-acyl-sn-glycero-3- phosphocholine (PC), a major component of cell membranes and a PAF precursor. Under resting conditions, acyltransferase activity is preferred. Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases. Also catalyzes the conversion of 1-acyl-sn-glycero-3-phosphocholine to 1,2- diacyl-sn-glycero-3-phosphocholine. {ECO:0000269|PubMed:20363836, ECO:0000269|PubMed:21498505}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:21498505}; Single-pass type II membrane protein {ECO:0000269|PubMed:21498505}. Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Lipid droplet {ECO:0000269|PubMed:21498505}.
Top Pathways	Ether lipid metabolism, Glycerophospholipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human LPCAT2 ELISA Kit (Sandwich ELISA) - LS-F8329 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.137 ng/ml Range 0.313-20 ng/ml

Mouse LPCAT2 ELISA Kit (Sandwich ELISA) - LS-F8439 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.108 ng/ml Range 0.313-20 ng/ml

Human LPCAT2 ELISA Kit (Sandwich ELISA) - LS-F12268 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 Range 0.313-20 ng/ml

Human LPCAT2 ELISA Kit - abx152226 from Abbexa Category ELISA Kit Sensitivity 0.58 ng/ml Range 1.563 ng/ml - 100 ng/ml

Lysophosphatidylcholine Acyltransferase 2 (LPCAT2), Human, ELISA Kit - SEG530Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.58ng/mL Range 1.56-100ng/mL

Lysophosphatidylcholine acyltransferase 2, LPCAT2, Human, ELISA Kit - E2228h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.312-20 ng/mL

lyso-platelet activating factor (lyso-PAF) , ELISA Kit - MBS2602960 from MyBioSource Category ELISA Kit Prices $275.00, $420.00, $1,615.00, $2,880.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.05 ng/ml. Range 10 ng/ml-0.156ng/ml

lysophosphatidylcholine acyltransferase 2, ELISA Kit - MBS9336725 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Lysophosphatidylcholine Acyltransferase 2 (LPCAT2), ELISA Kit - MBS2023456 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of LPCAT2 is typically less than 0.137ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.312-20ng/mL

Lysophosphatidylcholine Acyltransferase 2 (LPCAT2), ELISA Kit - MBS2023032 from MyBioSource Category ELISA Kit Prices $385.00, $575.00, $785.00, $3,210.00, $5,825.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of mouse LPCAT2 is typically less than 0.108ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.312-20ng/mL

Lysophosphatidylcholine Acyltransferase 2 (LPCAT2), ELISA Kit - MBS9307806 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Lysophosphatidylcholine Acyltransferase 2 (LPCAT2), ELISA Kit - MBS9308629 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) - SEG530Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.137ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) - SEG530Mu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.108ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) - SEG530Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.137ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Mouse LPCAT2 ELISA Kit (Custom ELISA) - LS-F19531 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.313-20 ng/ml

Rat LPCAT2 ELISA Kit (Custom ELISA) - LS-F19532 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.313-20 ng/ml

Human Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) ELISA Kit - EKU05716 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.137 ng/mL Range 0.312-20 ng/mL

Human Lysophosphatidylcholine acyltransferase 2 ELISA Kit - abx251509 from Abbexa Category ELISA Kit Range 0.312 ng/ml - 20 ng/ml

Lysophosphatidylcholine Acyltransferase 2 (LPCAT2), Human, ELISA Kit - DL-LPCAT2-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 1.56-100 ng/mL

Human LPCAT2 ELISA Kit - abx573977 from Abbexa Category ELISA Kit Sensitivity 0.58 ng/ml Range 1.563 ng/ml - 100 ng/ml

Human Lysophosphatidylcholine acyltransferase 2 ELISA Kit - EKE53435 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 0.15 ng/mL Range 0.312-20 ng/mL

LPCAT2 - EKH4340 from Nordic BioSite Sensitivity 0.188ng/ml Range 0.312-20ng/ml

LPCAT2 ELISA Kit (Human) (OKEH01577) - OKEH01577 from Aviva Systems Biology Category ELISA Kit Prices $420.00 Sizes 96 wells Sensitivity < 0.15 ng/mL Range 0.312 - 20 ng/mL

Human LPCAT2 ELISA Kit - E023212 from Biobool Category ELISA Kit Sensitivity 0.05 ng/ml.

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