Gene Symbol | RNASEH2C |
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Entrez Gene | 84153 |
Alt Symbol | AGS3, AYP1 |
Species | Human |
Gene Type | protein-coding |
Description | ribonuclease H2, subunit C |
Other Description | RNase H1 small subunit|RNase H2 subunit C|aicardi-Goutieres syndrome 3 protein|ribonuclease H2 subunit C|ribonuclease HI subunit C |
Swissprots | Q8TDP1 Q9H7F5 |
Accessions | AAO49176 EAW74433 EAW74434 EAW74435 Q8TDP1 AF312034 AAL87739 AF346606 AAO49177 AK024627 BAB14937 AK225131 AK297660 BAG60026 BC000831 BC023588 AAH23588 BC061891 BM921525 DQ892277 ABM83203 DQ895477 ABM86403 L08647 NM_032193 NP_115569 |
Function | Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. {ECO:0000269|PubMed:16845400, ECO:0000269|PubMed:21177858}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:16845400}. |
Top Pathways | DNA replication |
RNase HII-C (C-15) - sc-68227 from Santa Cruz Biotechnology
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RNase HII-C (D-17) - sc-68228 from Santa Cruz Biotechnology
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RNase HII-C (G-19) - sc-68230 from Santa Cruz Biotechnology
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RNase HII-C (V-20) - sc-68232 from Santa Cruz Biotechnology
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Anti-RNase H2 subunit C antibody - ab89726 from Abcam
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Anti-RNase H2 subunit C antibody - ab176197 from Abcam
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Anti-RNase H2 subunit C antibody - ab80880 from Abcam
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Anti-RNASEH2C / AGS3 Antibody (C-Terminus) - LS-C144859 from LifeSpan Bioscience
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Anti-RNASEH2C / AGS3 Antibody (aa80-108, AP) - LS-C285090 from LifeSpan Bioscience
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Anti-RNASEH2C / AGS3 Antibody (aa80-108, Biotin) - LS-C285093 from LifeSpan Bioscience
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Anti-RNASEH2C / AGS3 Antibody (aa80-108, APC) - LS-C285091 from LifeSpan Bioscience
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Anti-RNASEH2C / AGS3 Antibody (aa80-108, FITC) - LS-C285094 from LifeSpan Bioscience
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Anti-RNASEH2C / AGS3 Antibody (aa80-108, PE) - LS-C285096 from LifeSpan Bioscience
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Anti-RNASEH2C / AGS3 Antibody (aa80-108, Azide-free, HRP) - LS-C285095 from LifeSpan Bioscience
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Anti-RNASEH2C / AGS3 Antibody (aa87-116) - LS-C324754 from LifeSpan Bioscience
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Anti-RNASEH2C / AGS3 Antibody (Internal) - LS-C345276 from LifeSpan Bioscience
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Anti-RNASEH2C / AGS3 Antibody (aa80-108) - LS-C162672 from LifeSpan Bioscience
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RNASEH2C Antibody - NBP2-31792 from Novus Biologicals
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RNASEH2C Antibody (5D6) - H00084153-M02 from Novus Biologicals
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ANTI-RNH2C (CENTER) antibody produced in rabbit - SAB1301686 from Sigma-Aldrich
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Anti-RNASEH2C antibody produced in rabbit - HPA059703 from Sigma-Aldrich
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RNASEH2C Antibody - middle region (ARP73246_P050) - ARP73246_P050 from Aviva Systems Biology
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RNH2C-Antibody-Center - AP9303c from Abgent, a WuXi AppTec company
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RNASEH2C Antibody - middle region (OAAB05895) - OAAB05895 from Aviva Systems Biology
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RNASEH2C antibody - 70R-19915 from Fitzgerald
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