Gene Symbol | RNASEH2C |
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Entrez Gene | 84153 |
Alt Symbol | AGS3, AYP1 |
Species | Human |
Gene Type | protein-coding |
Description | ribonuclease H2, subunit C |
Other Description | RNase H1 small subunit|RNase H2 subunit C|aicardi-Goutieres syndrome 3 protein|ribonuclease H2 subunit C|ribonuclease HI subunit C |
Swissprots | Q8TDP1 Q9H7F5 |
Accessions | AAO49176 EAW74433 EAW74434 EAW74435 Q8TDP1 AF312034 AAL87739 AF346606 AAO49177 AK024627 BAB14937 AK225131 AK297660 BAG60026 BC000831 BC023588 AAH23588 BC061891 BM921525 DQ892277 ABM83203 DQ895477 ABM86403 L08647 NM_032193 NP_115569 |
Function | Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. {ECO:0000269|PubMed:16845400, ECO:0000269|PubMed:21177858}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:16845400}. |
Top Pathways | DNA replication |
Human RNase H2 subunit C full length protein - ab132876 from Abcam
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Human RNase H2 subunit C peptide - ab90249 from Abcam
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Human RNase H2 subunit C peptide - ab90250 from Abcam
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RNASEH2C / AGS3 Antibody Blocking Peptide - LS-E10055 from LifeSpan Bioscience
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Recombinant Human RNASEH2C Protein - H00084153-P01 from Novus Biologicals
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RNH2C-Antibody-Center-Blocking-Peptide - BP9303c from Abgent, a WuXi AppTec company
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RNASEH2C - H00084153-P01-10 from Acris Antibodies
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RNASEH2C - H00084153-P01-25 from Acris Antibodies
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RNASEH2C fusion protein - Ag9723 from Proteintech Group
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RNASEH2C fusion protein - ag9739 from Proteintech Group
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Recombinant Human RNASEH2C, His-tagged - RNASEH2C-2328H from Creative Biomart
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Recombinant Human Ribonuclease H2 subunit C(RNASEH2C) - CSB-YP837441HU CSB-EP837441HU CSB-BP837441HU CSB-MP837441HU from Cusabio
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RNASEH2C Protein - NBP2-31792PEP from Novus Biologicals
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RNASEH2C Peptide, Human - M34GP13357H from Creative Peptides
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Ribonuclease H2 subunit C (RNASEH2C), Recombinant Protein - MBS1280773 from MyBioSource
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RNASEH2C Recombinant Protein Antigen - NBP2-56902PEP from Novus Biologicals
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Recombinant Human AYP1 protein, GST-tagged - AYP1-1051H from Creative Biomart
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