| Gene Symbol | RNASEH2C |
|---|---|
| Entrez Gene | 84153 |
| Alt Symbol | AGS3, AYP1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ribonuclease H2, subunit C |
| Other Description | RNase H1 small subunit|RNase H2 subunit C|aicardi-Goutieres syndrome 3 protein|ribonuclease H2 subunit C|ribonuclease HI subunit C |
| Swissprots | Q8TDP1 Q9H7F5 |
| Accessions | AAO49176 EAW74433 EAW74434 EAW74435 Q8TDP1 AF312034 AAL87739 AF346606 AAO49177 AK024627 BAB14937 AK225131 AK297660 BAG60026 BC000831 BC023588 AAH23588 BC061891 BM921525 DQ892277 ABM83203 DQ895477 ABM86403 L08647 NM_032193 NP_115569 |
| Function | Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. {ECO:0000269|PubMed:16845400, ECO:0000269|PubMed:21177858}. |
| Subcellular Location | Nucleus {ECO:0000305}. |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:16845400}. |
| Top Pathways | DNA replication |
ribonuclease H2, subunit C, ELISA Kit - MBS9324458 from MyBioSource
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Human RNASEH2C ELISA Kit - E033612 from Biobool
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