GPC3

Gene Symbol	GPC3
Entrez Gene	2719
Alt Symbol	DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1
Species	Human
Gene Type	protein-coding
Description	glypican 3
Other Description	glypican proteoglycan 3|glypican-3|heparan sulphate proteoglycan|intestinal protein OCI-5|secreted glypican-3
Swissprots	Q2L880 C9JLE3 Q2L882 G3V1R0 P51654
Accessions	AAA98131 AAB87062 CAJ44931 CAO00500 CBF57584 EAX11769 EAX11770 EAX11771 P51654 AK222761 BAD96481 AK222766 BAD96486 AK300168 BAG61950 AK310196 AK310689 BC035972 AAH35972 BX329946 DB107651 DQ349136 ABC72125 DQ349137 ABC72126 DQ349138 ABC72127 DQ893658 ABM84584 DQ895822 ABM86748 JQ943686 AFM30911 L47125 AAA98132 L47176 AAB58806 U50410 AAA93471 Z37987 CAA86069 NM_001164617 NP_001158089 NM_001164618 NP_001158090 NM_001164619 NP_001158091 NM_004484 NP_004475
Function	Cell surface proteoglycan that bears heparan sulfate. Inhibits the dipeptidyl peptidase activity of DPP4. May be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs. May play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. May regulate growth and tumor predisposition. {ECO:0000269|PubMed:17549790}.
Subcellular Location	Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}; Extracellular side {ECO:0000250}.
Tissue Specificity	Highly expressed in lung, liver and kidney.
Top Pathways	Proteoglycans in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Glypican 3 peptide - ab111665 from Abcam Category Peptide Species Human

Human Glypican 3 protein fragment - ab114311 from Abcam Category Protein Source Wheat germ Species Human

Human Glypican 3 protein fragment - ab152426 from Abcam Category Protein Source Wheat germ Species Human

GPC3 / Glypican 3 Antibody Blocking Peptide - LS-E3617 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Glypican 3 Protein - H00002719-Q01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human Glypican 3 Protein - H00002719-Q02 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

GPC3-Antibody-C-term-Blocking-Peptide - BP14822b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Glypican 3 - 2119-GP-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Met1-His559 with a C-terminal 6-His tag

Recombinant Human Glypican 3, CF - 2119-GP-050/CF from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Met1-His559 with a C-terminal 6-His tag

Human Glypican 3 protein - orb83512 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

GPC3 Blocking Peptide - 33R-3080 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human Glypican 3 Protein - abx066892 from Abbexa Category Protein Source E.coli Species Human

Human GPC3 Protein (Active) - abx060263 from Abbexa Category Protein Source Human Species Human

Human GPC3 Protein (Active) - abx060155 from Abbexa Category Protein Source Human Species Human

Glypican-3 / GPC3 - H00002719-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Glypican-3 / GPC3 - H00002719-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Glypican-3 / GPC3 - H00002719-Q02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Glypican-3 / GPC3 - H00002719-Q02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Glypican 3 Recombinant Protein - 96-360 from ProSci Category Protein Prices $375.00 Sizes 100 µg Source HEK293 cells Species Human

GPC3 fusion protein - ag1433 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

GPC3 fusion protein - ag10116 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

GPC3 fusion protein - ag10129 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

GPC3 (144 - 152) - 62604 from NeoScientific Category Peptide Prices $75.00, $125.00, $250.00 Sizes 5 mg, 10 mg, 25 mg

GPC3 (298 - 306), mouse - 62605 from NeoScientific Category Peptide Prices $108.00, $180.00, $250.00 Sizes 5 mg, 10 mg, 25 mg Species Mouse

Glypican-3 Peptide - 350497 from ABBIOTEC Category Peptide Prices $50.00 Sizes 100 µg

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