GPC3

Gene Symbol GPC3
Entrez Gene 2719
Alt Symbol DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1
Species Human
Gene Type protein-coding
Description glypican 3
Other Description glypican proteoglycan 3|glypican-3|heparan sulphate proteoglycan|intestinal protein OCI-5|secreted glypican-3
Swissprots Q2L880 C9JLE3 Q2L882 G3V1R0 P51654
Accessions AAA98131 AAB87062 CAJ44931 CAO00500 CBF57584 EAX11769 EAX11770 EAX11771 P51654 AK222761 BAD96481 AK222766 BAD96486 AK300168 BAG61950 AK310196 AK310689 BC035972 AAH35972 BX329946 DB107651 DQ349136 ABC72125 DQ349137 ABC72126 DQ349138 ABC72127 DQ893658 ABM84584 DQ895822 ABM86748 JQ943686 AFM30911 L47125 AAA98132 L47176 AAB58806 U50410 AAA93471 Z37987 CAA86069 NM_001164617 NP_001158089 NM_001164618 NP_001158090 NM_001164619 NP_001158091 NM_004484 NP_004475
Function Cell surface proteoglycan that bears heparan sulfate. Inhibits the dipeptidyl peptidase activity of DPP4. May be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs. May play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. May regulate growth and tumor predisposition. {ECO:0000269|PubMed:17549790}.
Subcellular Location Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}; Extracellular side {ECO:0000250}.
Tissue Specificity Highly expressed in lung, liver and kidney.
Top Pathways Proteoglycans in cancer

glypican-3 CRISPR/Cas9 KO Plasmid (h) - sc-400256 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

glypican-3 HDR Plasmid (h) - sc-400256-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

glypican-3 Double Nickase Plasmid (h) - sc-400256-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

glypican-3 Double Nickase Plasmid (h2) - sc-400256-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

glypican-3 CRISPR Activation Plasmid (h) - sc-400256-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

glypican-3 CRISPR Activation Plasmid (h2) - sc-400256-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

glypican-3 Lentiviral Activation Particles (h) - sc-400256-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

glypican-3 Lentiviral Activation Particles (h2) - sc-400256-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

glypican-3 siRNA (h) - sc-40640 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

glypican-3 shRNA Plasmid (h) - sc-40640-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

glypican-3 shRNA (h) Lentiviral Particles - sc-40640-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU001531 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9515 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9515 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

GPC3 siRNA (Human) - CRH1812 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GPC3 - MBS8200895 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GPC3 (NM_004484.3) - SHH305762 from Creative biogene

Category siRNA
Species Reactivities Human

Human GPC3 siRNA - orb262314 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GPC3 shRNA Plasmid (Human) - CHH1812 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GPC3 miRNA 3'UTR clone - MiUTR3H-02512 from Creative biogene

Species Reactivities Human

GPC3 miRNA 3'UTR clone - MiUTR3H-02513 from Creative biogene

Species Reactivities Human

GPC3 miRNA 3'UTR clone - MiUTR3H-02514 from Creative biogene

Species Reactivities Human

GPC3 miRNA 3'UTR clone - MiUTR3H-02515 from Creative biogene

Species Reactivities Human
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