TNPO2

Gene Symbol	TNPO2
Entrez Gene	30000
Alt Symbol	IPO3, KPNB2B, TRN2
Species	Human
Gene Type	protein-coding
Description	transportin 2
Other Description	importin 3|karyopherin beta 2b, transportin|karyopherin beta-2b|transportin 2 (importin 3, karyopherin beta 2b)|transportin-2
Swissprots	Q6IN77 O14787 O14655
Accessions	CCQ43422 EAW84299 EAW84300 EAW84301 O14787 AB210011 BAE06093 AF007748 AAB71349 AF019039 AAB83973 AK022217 AK056183 BAG51640 AK299485 BAG61447 AK307632 AL832114 BC018314 AAH18314 BC063679 BC072420 AAH72420 DA100622 DA808781 DC377831 DC407313 F15550 NM_001136195 NP_001129667 NM_001136196 NP_001129668 NM_013433 NP_038461
Function	Probably functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TNPO2 protein fragment - ab153311 from Abcam Category Protein Source Wheat germ Species Human

TNPO2/ Importin Antibody Blocking Peptide - LS-E19825 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TNPO2/ Importin Antibody Blocking Peptide - LS-E19826 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human TNPO2 Protein - H00030000-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Transportin 2 Blocking Peptide - 33R-5883 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Transportin 2 Blocking Peptide - 33R-5534 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Transportin-2 (TNPO2) - H00030000-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Transportin-2 (TNPO2) - H00030000-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TNPO2 fusion protein - Ag12229 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human TNPO2, His-tagged - TNPO2-3337H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Transportin 2 (TNPO2) - RPD196Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Transportin 2 (TNPO2) - RPD196Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Transportin-2(TNPO2) ,partial - CSB-YP024021HU CSB-EP024021HU CSB-BP024021HU CSB-MP024021HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Transportin 2 Protein (Recombinant) - abx168145 from Abbexa Category Protein Source Human Species Human

TNPO2-Antibody-N-term-Blocking-Peptide - BP9561b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TNPO2 Peptide, Human - M34GP16406H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Transportin 2 (TNPO2) - RPU52215 from Biomatik Category Protein Prices $185.00, $378.00, $578.00, $688.80 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

TNPO2 Recombinant Protein (OPCD07623) - OPCD07623 from Aviva Systems Biology Category Protein Source E.coli Species Human

TNPO2 Recombinant Protein Antigen - NBP2-57553PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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