TNPO2

Gene Symbol TNPO2
Entrez Gene 30000
Alt Symbol IPO3, KPNB2B, TRN2
Species Human
Gene Type protein-coding
Description transportin 2
Other Description importin 3|karyopherin beta 2b, transportin|karyopherin beta-2b|transportin 2 (importin 3, karyopherin beta 2b)|transportin-2
Swissprots Q6IN77 O14787 O14655
Accessions CCQ43422 EAW84299 EAW84300 EAW84301 O14787 AB210011 BAE06093 AF007748 AAB71349 AF019039 AAB83973 AK022217 AK056183 BAG51640 AK299485 BAG61447 AK307632 AL832114 BC018314 AAH18314 BC063679 BC072420 AAH72420 DA100622 DA808781 DC377831 DC407313 F15550 NM_001136195 NP_001129667 NM_001136196 NP_001129668 NM_013433 NP_038461
Function Probably functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.

karyopherin β2/2B (A-11) - sc-365179 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
karyopherin β2/2B (A-11): sc-365179. Western blot analysis of karyopherin β2/2B expression in Jurkat (A) and A-431 (B) whole cell lysates.

Anti-TNPO2 antibody - ab194450 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Anti-TNPO2 antibody (ab194450) at 1/500 dilution + HeLa S3 nuclear extract at 50 µgdeveloped using the ECL technique

Anti-TNPO2 antibody - ab127165 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TNPO2 antibody (ab127165) at 1/1000 dilutionLane 1 : 293T cell lysate Lane 2 : A431 cell lysate Lysates/proteins at 30 µg per lane.

Anti-TNPO2 antibody - ab82681 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TNPO2 antibody (ab82681) at 1 µg/ml + MCF-7 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-TNPO2 antibody - ab82655 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TNPO2 antibody (ab82655) at 1 µg/ml (5% skim milk / PBS buffer) + Jurkat cell lysate. at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-TNPO2 / Importin Antibody (N-Terminus) - LS-C81968 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MCF7 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-TNPO2 / Importin Antibody (aa612-661) - LS-C81969 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Jurkat cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

TNPO2 Antibody - NBP1-52896 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: TNPO2 Antibody [NBP1-52896] - Jurkat cell lysate, concentration 0.2-1 ug/ml.

TNPO2 Antibody - NBP2-20676 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: TNPO2 Antibody [NBP2-20676] - Sample (30 ug of whole cell lysate) A: 293T B: A431 7. 5% SDS PAGE gel, diluted at 1:1000.

TNPO2 Antibody - H00030000-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: TNPO2 Antibody [H00030000-A01] - TNPO2 polyclonal antibody (A01), Lot # 060619JCS1 Western Blot analysis of TNPO2 expression in Hela NE ( Cat # L013V3 ).

Anti-TNPO2 (N-terminal) antibody produced in rabbit - SAB4200032 from Sigma-Aldrich

Prices $61.10, $360.00
Sizes 25 µl, 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Predominant nuclear localization of TNPO2 in HEK-293T cells. Cells were fixed and stained with 5 μg/mL Rabbit Anti-TNPO2 (N-terminal) (<B>Cat. No. SAB4200032</B>) followed by Goat Anti-Rabbit, Cy3 conjugated (×40 magnification).

Anti-TNPO2 (ab1) antibody produced in rabbit - SAB2102504 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-TNPO2 (ab1): <B>Cat. No.SAB2102504</B>: TNPO2 in MCF7 cell lysate with TNPO2 antibody at 1.0 μg/mL.

Anti-TNPO2 (C-terminal) antibody produced in rabbit - SAB4200031 from Sigma-Aldrich

Prices $61.10, $360.00
Sizes 25 µl, 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Predominant nuclear localization of TNPO2 in HEK-293T cells over-expressing human TNPO2. Cells were stained with Rabbit Anti-TNPO2 (C-terminal) (<B>Cat. No. SAB4200031</B>) followed by Goat Anti-Rabbit, Cy3 conjugated. The cells were counterstained with DAPI (blue) to stain nuclei (×40 magnification).

TNPO2 antibody - N-terminal region (ARP54955_P050) - ARP54955_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TNPO2 antibody - C-terminal region (ARP54956_P050) - ARP54956_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TNPO2 Polyclonal Antibody - A4681 from ABclonal

Prices $200.00, $480.00
Sizes 50 µg, 200 µg
Host Rabbit
Clonality Polyclonal

Transportin 2 antibody - 70R-2301 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

TNPO2 antibody - 70R-20910 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Transportin 2 antibody - 70R-2016 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

TNPO2 Antibody - abx003532 from Abbexa

Host Rabbit
Clonality Polyclonal

TNPO2 antibody - 17831-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of MCF-7 cells, using TNPO2 antibody 17831-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

Transportin-2 (TNPO2) antibody - H00030000-A01 from Acris Antibodies

Prices $300.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
TNPO2 polyclonal antibody (A01), Lot # 060619JCS1. Western Blot analysis of TNPO2 expression in PC-12.

Anti-TNPO2, Polyclonal Antibody - 25-A4681 from ARP American Research Products

Prices $379.00, $549.00
Sizes 100 µg, 200 µg
Host Rabbit
Clonality Polyclonal

TNPO2 Antibody - 26-953 from ProSci

Prices $315.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Antibody used in WB on Human MCF-7 at 0.2-1 ug/ml.

TNPO2 Antibody - 26-954 from ProSci

Prices $315.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Antibody used in WB on Human Jurkat 0.2-1 ug/ml.
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