TNPO2

Gene Symbol TNPO2
Entrez Gene 30000
Alt Symbol IPO3, KPNB2B, TRN2
Species Human
Gene Type protein-coding
Description transportin 2
Other Description importin 3|karyopherin beta 2b, transportin|karyopherin beta-2b|transportin 2 (importin 3, karyopherin beta 2b)|transportin-2
Swissprots Q6IN77 O14787 O14655
Accessions CCQ43422 EAW84299 EAW84300 EAW84301 O14787 AB210011 BAE06093 AF007748 AAB71349 AF019039 AAB83973 AK022217 AK056183 BAG51640 AK299485 BAG61447 AK307632 AL832114 BC018314 AAH18314 BC063679 BC072420 AAH72420 DA100622 DA808781 DC377831 DC407313 F15550 NM_001136195 NP_001129667 NM_001136196 NP_001129668 NM_013433 NP_038461
Function Probably functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.

transportin 2 CRISPR/Cas9 KO Plasmid (h) - sc-412067 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

transportin 2 HDR Plasmid (h) - sc-412067-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

transportin 2 Double Nickase Plasmid (h) - sc-412067-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

transportin 2 Double Nickase Plasmid (h2) - sc-412067-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

transportin 2 CRISPR Activation Plasmid (h) - sc-412067-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

transportin 2 CRISPR Activation Plasmid (h2) - sc-412067-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

transportin 2 Lentiviral Activation Particles (h) - sc-412067-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

transportin 2 Lentiviral Activation Particles (h2) - sc-412067-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

karyopherin β2B siRNA (h) - sc-97580 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

karyopherin β2B shRNA Plasmid (h) - sc-97580-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

karyopherin β2B shRNA (h) Lentiviral Particles - sc-97580-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU086521 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21794 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

TNPO2 siRNA (Human) - CRH9328 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TNPO2 RNAi - H00030000-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

TNPO2 - MBS828574 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TNPO2 (NM_013433.4) - SHH432488 from Creative biogene

Category siRNA
Species Reactivities Human

Human TNPO2 siRNA - orb269830 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TNPO2 shRNA Plasmid (Human) - CHH9328 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TNPO2 miRNA 3'UTR clone - MiUTR4H-TG09251 from Creative biogene

Species Reactivities Human
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