POLR1B

Gene Symbol POLR1B
Entrez Gene 84172
Alt Symbol RPA135, RPA2, Rpo1-2
Species Human
Gene Type protein-coding
Description polymerase (RNA) I polypeptide B, 128kDa
Other Description DNA-directed RNA polymerase I 135 kDa polypeptide|DNA-directed RNA polymerase I 135kDa polypeptide|DNA-directed RNA polymerase I subunit RPA2|RNA polymerase I subunit 2
Swissprots B7Z823 B7Z6Y7 Q6ZRR2 Q2TAM4 F8W898 F5GZX4 Q9H9D3 Q585T5 Q9H9Y6
Accessions AAX81999 EAW73590 EAW73591 EAW73592 EAW73593 Q9H9Y6 AA484631 AK001678 BAA91831 AK022533 BAB14082 AK022890 BAB14296 AK025574 BAB15175 AK128044 BAC87247 AK172817 AK294027 BAH11652 AK301178 BAH13423 AK302814 BAH13809 BC004882 AAH04882 BC073857 AAH73857 BC096748 AAH96748 BC110833 AAI10834 BC150139 BX647360 BX647683 NM_001137604 NP_001131076 NM_001282772 NP_001269701 NM_001282774 NP_001269703 NM_001282776 NP_001269705 NM_001282777 NP_001269706 NM_001282779 NP_001269708 NM_019014 NP_061887
Function DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity). {ECO:0000250}.
Subcellular Location Nucleus, nucleolus {ECO:0000269|PubMed:11250903}.
Top Pathways Purine metabolism, RNA polymerase, Pyrimidine metabolism

Human RPA2 gene - orb92277 from Biorbyt

Prices $255.00
Sizes 10 μg
Species Human

Human POLR1B cDNA clone(NM_001137604.1) - CDFH014684 from Creative Biomart

Species Human
Accession NM_001137604.1

Human POLR1B ORF Clone(NM_001137604.1) - CDCR350859 from Creative Biomart

Species Human
Accession NM_001137604.1

Human POLR1B ORF Clone(NM_001137604.1) - CDCR350860 from Creative Biomart

Species Human
Accession NM_001137604.1

human POLR1B ORF clone (NM_001137604.1) - CDCH065858 from Creative biogene

Species Human

Human POLR1B cDNA Clone(NM_001137604.1) - CDFH014684 from Creative biogene

Species Human
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