POLR1B

Gene Symbol	POLR1B
Entrez Gene	84172
Alt Symbol	RPA135, RPA2, Rpo1-2
Species	Human
Gene Type	protein-coding
Description	polymerase (RNA) I polypeptide B, 128kDa
Other Description	DNA-directed RNA polymerase I 135 kDa polypeptide|DNA-directed RNA polymerase I 135kDa polypeptide|DNA-directed RNA polymerase I subunit RPA2|RNA polymerase I subunit 2
Swissprots	B7Z823 B7Z6Y7 Q6ZRR2 Q2TAM4 F8W898 F5GZX4 Q9H9D3 Q585T5 Q9H9Y6
Accessions	AAX81999 EAW73590 EAW73591 EAW73592 EAW73593 Q9H9Y6 AA484631 AK001678 BAA91831 AK022533 BAB14082 AK022890 BAB14296 AK025574 BAB15175 AK128044 BAC87247 AK172817 AK294027 BAH11652 AK301178 BAH13423 AK302814 BAH13809 BC004882 AAH04882 BC073857 AAH73857 BC096748 AAH96748 BC110833 AAI10834 BC150139 BX647360 BX647683 NM_001137604 NP_001131076 NM_001282772 NP_001269701 NM_001282774 NP_001269703 NM_001282776 NP_001269705 NM_001282777 NP_001269706 NM_001282779 NP_001269708 NM_019014 NP_061887
Function	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus, nucleolus {ECO:0000269|PubMed:11250903}.
Top Pathways	Purine metabolism, RNA polymerase, Pyrimidine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human POLR1B protein fragment - ab164514 from Abcam Category Protein Source Wheat germ Species Human

POLR1B Antibody Blocking Peptide - LS-E1718 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

POLR1B Antibody Blocking Peptide - LS-E17662 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RPA2 / RFA2 / RPA34 Antibody Blocking Peptide - LS-E22822 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RPA2 / RFA2 / RPA34 Antibody Blocking Peptide - LS-E9945 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RPA2 Recombinant Protein - H00006118-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human POLR1B Protein - H00084172-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human RPA2 Protein - NBP1-50878 from Novus Biologicals Category Protein Prices $349.00, $969.00 Sizes 50 µg, 250 µg Source E. coli Species Human

POLR1B-Antibody-N-term-Blocking-peptide - BP12495a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human RPA2 protein - orb169208 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E. coli

POLR1B Blocking Peptide - 33R-8358 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

POLR1B - H00084172-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

POLR1B - H00084172-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

POLR1B fusion protein - ag12375 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

POLR1B fusion protein - Ag13306 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

RPA2 fusion protein - Ag24783 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

RPA2 Human Protein - GWB-BSP619 from Genway Biotech Category Protein Prices $75.00, $165.00, $6,190.00 Sizes 2 μg, 10 μg, 1000 μg Source Escherichia Coli. Species Human

Recombinant Human DNA-directed RNA polymerase I subunit RPA2(POLR1B) ,partial - CSB-YP872528HU CSB-EP872528HU CSB-BP872528HU CSB-MP872528HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

RPA2 Recombinant Protein Antigen - NBP1-89524PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

RPA2 Protein - NBP1-89523PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

RPA2 (pS33) Blocking Peptide - abx162023 from Abbexa Category Peptide Species Human, Mouse, Rat

RPA2 (pT21) Blocking Peptide - abx162022 from Abbexa Category Peptide Species Human, Rat

POLR1B Recombinant Protein Antigen - NBP2-48675PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

POLR1B Peptide, Human - M34GP12085H from Creative Peptides Category Peptide Source Synthetic. Species Human

RPA2 Peptide, Human - M34GP13480H from Creative Peptides Category Peptide Source Synthetic. Species Human

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