KMO

Gene Symbol	KMO
Entrez Gene	8564
Alt Symbol	dJ317G22.1
Species	Human
Gene Type	protein-coding
Description	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
Other Description	kynurenine 3-hydroxylase|kynurenine 3-monooxygenase
Swissprots	A2A2V0 O15229 Q5SY09 Q5SY07 A2A2U9 Q5SY08 A2A2U8
Accessions	EAW70094 EAW70095 EAW70096 O15229 AF056032 AAC62615 AI262990 AK291558 BAF84247 AK310937 AU137977 BC005297 AAH05297 BP276365 CB989076 DB373228 Y13153 CAA73613 XM_005273337 XP_005273394 XM_005273338 XP_005273395 NM_003679 NP_003670
Function	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.
Subcellular Location	Mitochondrion outer membrane {ECO:0000255|HAMAP-Rule:MF_03018, ECO:0000269|PubMed:9237672}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_03018, ECO:0000269|PubMed:9237672}.
Tissue Specificity	Highest levels in placenta and liver. Detectable in kidney. {ECO:0000269|PubMed:9237672}.
Top Pathways	Tryptophan metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human KMO ELISA Kit (Sandwich ELISA) - LS-F8353 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.3 ng/ml Range 0.781-50 ng/ml

Rat KMO ELISA Kit (Sandwich ELISA) - LS-F11898 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.78 Range 0.781-50 ng/ml

Human KMO ELISA Kit - abx152142 from Abbexa Category ELISA Kit Sensitivity 0.30 ng/ml Range 0.781 ng/ml - 50 ng/ml

Kynurenine 3-monooxygenase (KMO), Human, ELISA Kit - E01K0092 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Kynurenine 3-monooxygenase, KMO, Human, ELISA Kit - E13545h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Kynurenine-3-Monooxygenase (KMO), Human, ELISA Kit - SEH755Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.24ng/mL Range 0.78-50ng/mL

Kynurenine 3 monooxygenase (KMO), ELISA Kit - MBS7225570 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kynurenine 3-monooxygenase (KMO), ELISA Kit - MBS7252237 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kynurenine 3-monooxygenase (KMO), ELISA Kit - MBS7214664 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kynurenine 3-monooxygenase (KMO), ELISA Kit - MBS7217235 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kynurenine 3-monooxygenase (KMO), ELISA Kit - MBS7250771 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kynurenine 3-monooxygenase (KMO), ELISA Kit - MBS7211872 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Kynurenine 3-monooxygenase (KMO), ELISA Kit - MBS7244385 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kynurenine 3-monooxygenase (KMO), ELISA Kit - MBS7232910 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kynurenine 3-monooxygenase (KMO), ELISA Kit - MBS7243164 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kynurenine 3-monooxygenase (KMO), ELISA Kit - MBS7219903 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kynurenine 3-monooxygenase (KMO), ELISA Kit - MBS7211232 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kynurenine 3-monooxygenase (KMO), ELISA Kit - MBS7206118 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kynurenine-3-Monooxygenase (KMO), ELISA Kit - MBS2025025 from MyBioSource Category ELISA Kit Prices $405.00, $605.00, $820.00, $3,375.00, $6,125.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.118ng/mL. Range 0.313-20ng/mL

Kynurenine-3-Monooxygenase (KMO), ELISA Kit - MBS2024073 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.30ng/mL. Range 0.781-50ng/mL

ELISA Kit for Kynurenine-3-Monooxygenase (KMO) - SEH755Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.30ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA’s were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

ELISA Kit for Kynurenine-3-Monooxygenase (KMO) - SEH755Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.118ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for Kynurenine-3-Monooxygenase (KMO) - SEH755Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.30ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA's were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

Human KMO ELISA Kit (Custom ELISA) - LS-F16992 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.781-50 ng/ml

Mouse KMO ELISA Kit (Custom ELISA) - LS-F16994 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.781-50 ng/ml

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