LSM1

Gene Symbol LSM1
Entrez Gene 27257
Alt Symbol CASM, YJL124C
Species Human
Gene Type protein-coding
Description LSM1, U6 small nuclear RNA associated
Other Description LSM1 homolog, U6 small nuclear RNA associated|U6 snRNA-associated Sm-like protein LSm1|cancer-associated Sm-like protein|small nuclear ribonuclear CaSm
Swissprots O15116 B2R5E6
Accessions CBM42914 CBV35647 EAW63332 EAW63333 O15116 AF000177 AAB62189 AF147348 AJ238094 CAB45865 AK312159 BAG35093 BC001767 AAH01767 BE670269 BP376421 BU521199 BU941962 NM_014462 NP_055277 NR_045492 NR_045493
Function Plays a role in replication-dependent histone mRNA degradation. Binds specifically to the 3'-terminal U-tract of U6 snRNA. {ECO:0000269|PubMed:18172165}.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Has elevated expression in pancreatic cancer and in several cancer-derived cell lines.
Top Pathways RNA degradation

LSm1 (A-4) - sc-398623 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
LSm1 (A-4): sc-398623. Western blot analysis of LSm1 expression in RT-4 (A), U-251-MG (B) and K-562 (C) whole cell lysates and human liver tissue extract (D).

LSm1 (A-9) - sc-373685 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
LSm1 (A-9): sc-373685. Western blot analysis of LSm1 expression in RT-4 (A), U-251-MG (B) and K-562 (C) whole cell lysates and human liver tissue extract (D).

LSm1 (C-16) - sc-54088 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LSm1 (C-16): sc-54088. Western blot analysis of human recombinant LSm1 fusion protein.

LSm1 (FL-133) - sc-67365 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
LSm1 (FL-133): sc-67365. Western blot analysis of human recombinant LSm1 fusion protein.

LSm1 (K-14) - sc-54089 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

LSm1 (Q-19) - sc-54090 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LSm1 (Q-19): sc-54090. Western blot analysis of human recombinant LSm1 fusion protein.

Anti-LSM1 antibody - ab167194 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-LSM1 antibody (ab167194) at 1 µg/ml + K562 cell lysate at 50 µgSecondaryGoat anti-mouse HRP conjugated antibody at 1/2500 dilution

Anti-LSM1 antibody - ab37463 from Abcam

Prices $406.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal
Anti-LSM1 antibody (ab37463) at 1/2000 dilution + E coli-derived fusion proteinSecondaryGoat anti-IgY-HRP at 1/1000 dilution

Anti-LSM1 antibody - ab82227 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-LSM1 antibody (ab82227) at 1/50 dilution + mouse kidney tissue lysates at 35 µg

Anti-LSM1 antibody - ab82226 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-LSM1 antibody (ab82226) at 1/50 dilution + Hela cell line lysates at 35 µg

Anti-LSM1 antibody - ab191526 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-LSM1 antibody (ab191526)Lane 1 : HeLa whole cell lysateLane 2 : HEK293T whole cell lysate

Anti-LSM1 antibody [1F5] - ab118990 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1F5
All lanes : Anti-LSM1 antibody [1F5] (ab118990) at 1/500 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY LSM1 cDNALysates/proteins at 5 µg per lane.

Anti-LSM1 antibody - Aminoterminal end - ab56083 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LSM1 Antibody (clone 5C6) - LS-C173080 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5C6
IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-LSM1 mouse monoclonal antibody.

Anti-LSM1 Antibody (N-Terminus) - LS-C46818 from LifeSpan Bioscience

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LSM1 Antibody (aa1-133) - LS-C8539 from LifeSpan Bioscience

Prices $475.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal

Anti-LSM1 Antibody (aa34-134) - LS-C308824 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-LSM1 Antibody - LS-C340897 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LSM1 Antibody - LS-C334429 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of HeLa cell lines, using LSM1 antibody.

Anti-LSM1 Antibody (aa33-61) - LS-C97365 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of anti-LSM1 Antibody in mouse kidney tissue lysates (35 ug/lane). LSM1(arrow) was detected using the purified antibody.

Anti-LSM1 Antibody (clone 1F5) - LS-C337400 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1F5
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LSM1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LSM1.

Anti-LSM1 Antibody (aa103-133) - LS-C97364 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with LSM1 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-LSM1 Antibody (aa1-133, clone 1A9) - LS-C337403 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1A9
Anti-LSM1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LSM1.

Anti-LSM1 Antibody (C-Terminus) IHC-plus™ - LS-B5714 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-LSM1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5714 concentration 5 ug/ml.

Anti-LSM1 Antibody (clone 5E6) - LS-C173081 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5E6
Anti-LSM1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LSM1.
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