Gene Symbol | LSM1 |
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Entrez Gene | 27257 |
Alt Symbol | CASM, YJL124C |
Species | Human |
Gene Type | protein-coding |
Description | LSM1, U6 small nuclear RNA associated |
Other Description | LSM1 homolog, U6 small nuclear RNA associated|U6 snRNA-associated Sm-like protein LSm1|cancer-associated Sm-like protein|small nuclear ribonuclear CaSm |
Swissprots | O15116 B2R5E6 |
Accessions | CBM42914 CBV35647 EAW63332 EAW63333 O15116 AF000177 AAB62189 AF147348 AJ238094 CAB45865 AK312159 BAG35093 BC001767 AAH01767 BE670269 BP376421 BU521199 BU941962 NM_014462 NP_055277 NR_045492 NR_045493 |
Function | Plays a role in replication-dependent histone mRNA degradation. Binds specifically to the 3'-terminal U-tract of U6 snRNA. {ECO:0000269|PubMed:18172165}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Has elevated expression in pancreatic cancer and in several cancer-derived cell lines. |
Top Pathways | RNA degradation |
Human LSM1 full length protein - ab101157 from Abcam
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LSM1 Antibody Blocking Peptide - LS-E14943 from LifeSpan Bioscience
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LSM1 Antibody Blocking Peptide - LS-E7161 from LifeSpan Bioscience
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LSM1 Antibody Blocking Peptide - LS-E7162 from LifeSpan Bioscience
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LSM1 Partial Recombinant Protein - H00027257-Q01 from Novus Biologicals
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LSM1 Recombinant Protein - H00027257-P01 from Novus Biologicals
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Recombinant Human LSM1 Protein - NBP1-49169 from Novus Biologicals
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LSM1-Antibody-Center-Blocking-Peptide - BP2863c from Abgent, a WuXi AppTec company
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LSM1-Antibody-C-term-Blocking-Peptide - BP2863b from Abgent, a WuXi AppTec company
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LSM1 Protein (OPPA02585) - OPPA02585 from Aviva Systems Biology
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Human LSM1 protein - orb168748 from Biorbyt
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Human LSM1 protein (His Tag) - orb139296 from Biorbyt
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LSM1 Blocking Peptide - 33R-8375 from Fitzgerald
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LSM1 protein (His tag) - 80R-1496 from Fitzgerald
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LSM1 Blocking Peptide - abx064252 from Abbexa
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LSM1 (1-133, His-tag) - AR09672PU-L from Acris Antibodies
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LSM1 (1-133, His-tag) - AR09672PU-N from Acris Antibodies
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LSM1 - H00027257-P01-02 from Acris Antibodies
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LSM1 - H00027257-Q01-10 from Acris Antibodies
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LSM1 - H00027257-Q01-25 from Acris Antibodies
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LSM1 Homolog, U6 Small Nuclear RNA Associated, Human Recombinant - 228-13012-1 from RayBiotech
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Recombinant Human LSM1 Homolog, U6 Small Nuclear RNA Associated - 228-13012-2 from RayBiotech
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Recombinant Human LSM1 Homolog, U6 Small Nuclear RNA Associated - 228-13012-3 from RayBiotech
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LSM1, 1-133aa, Human, His tag, E.coli - 01-LSM-1 from ARP American Research Products
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U6 snRNA-Associated Sm-Like Protein LSm1, LSM1, Human, Recombinant - 19-C262 from ARP American Research Products
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