Gene Symbol | LSM1 |
---|---|
Entrez Gene | 27257 |
Alt Symbol | CASM, YJL124C |
Species | Human |
Gene Type | protein-coding |
Description | LSM1, U6 small nuclear RNA associated |
Other Description | LSM1 homolog, U6 small nuclear RNA associated|U6 snRNA-associated Sm-like protein LSm1|cancer-associated Sm-like protein|small nuclear ribonuclear CaSm |
Swissprots | O15116 B2R5E6 |
Accessions | CBM42914 CBV35647 EAW63332 EAW63333 O15116 AF000177 AAB62189 AF147348 AJ238094 CAB45865 AK312159 BAG35093 BC001767 AAH01767 BE670269 BP376421 BU521199 BU941962 NM_014462 NP_055277 NR_045492 NR_045493 |
Function | Plays a role in replication-dependent histone mRNA degradation. Binds specifically to the 3'-terminal U-tract of U6 snRNA. {ECO:0000269|PubMed:18172165}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Has elevated expression in pancreatic cancer and in several cancer-derived cell lines. |
Top Pathways | RNA degradation |