COPRS

Gene Symbol COPRS
Entrez Gene 55352
Alt Symbol C17orf79, COPR5, HSA272196, TTP1
Species Human
Gene Type protein-coding
Description coordinator of PRMT5, differentiation stimulator
Other Description cooperator of PRMT5|coordinator of PRMT5 and differentiation stimulator
Swissprots A6NP14 Q96EF5 Q9NQ92 Q96P75 E1P656
Accessions EAW80260 EAW80261 EAW80262 EAW80263 Q9NQ92 AF407672 AAK97661 AJ272196 CAB77267 AK024772 BC012386 AAH12386 BC035483 BQ671018 DB472863 XM_005258000 XP_005258057 NM_018405 NP_060875
Function Histone-binding protein required for histone H4 methyltransferase activity of PRMT5. Specifically required for histone H4 'Arg-3' methylation mediated by PRMT5, but not histone H3 'Arg-8' methylation, suggesting that it modulates the substrate specificity of PRMT5. Specifically interacts with the N-terminus of histone H4 but not with histone H3, suggesting that it acts by promoting the association between histone H4 and PRMT5. Involved in CCNE1 promoter repression. Plays a role in muscle cell differentiation by modulating the recruitment of PRMT5 to the promoter of genes involved in the coordination between cell cycle exit and muscle differentiation (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000269|PubMed:18404153}.

COPRS overexpression lysate - LY413077 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

C17orf79 293 Cell Lysate - 406344 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

COPR5 Overexpression Lysate (Native) - NBL1-08245 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg

C17orf79 Over-expression Lysate Product - GWB-ABF5C5 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Panoply™ Human C17ORF79 Knockdown Stable Cell Line - CSC-DC001801 from Creative biogene

Category Cell Line
Species Human
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