COPRS

Gene Symbol COPRS
Entrez Gene 55352
Alt Symbol C17orf79, COPR5, HSA272196, TTP1
Species Human
Gene Type protein-coding
Description coordinator of PRMT5, differentiation stimulator
Other Description cooperator of PRMT5|coordinator of PRMT5 and differentiation stimulator
Swissprots A6NP14 Q96EF5 Q9NQ92 Q96P75 E1P656
Accessions EAW80260 EAW80261 EAW80262 EAW80263 Q9NQ92 AF407672 AAK97661 AJ272196 CAB77267 AK024772 BC012386 AAH12386 BC035483 BQ671018 DB472863 XM_005258000 XP_005258057 NM_018405 NP_060875
Function Histone-binding protein required for histone H4 methyltransferase activity of PRMT5. Specifically required for histone H4 'Arg-3' methylation mediated by PRMT5, but not histone H3 'Arg-8' methylation, suggesting that it modulates the substrate specificity of PRMT5. Specifically interacts with the N-terminus of histone H4 but not with histone H3, suggesting that it acts by promoting the association between histone H4 and PRMT5. Involved in CCNE1 promoter repression. Plays a role in muscle cell differentiation by modulating the recruitment of PRMT5 to the promoter of genes involved in the coordination between cell cycle exit and muscle differentiation (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000269|PubMed:18404153}.

C17orf79 CRISPR/Cas9 KO Plasmid (h) - sc-412527 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C17orf79 HDR Plasmid (h) - sc-412527-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C17orf79 Double Nickase Plasmid (h) - sc-412527-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C17orf79 Double Nickase Plasmid (h2) - sc-412527-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C17orf79 CRISPR Activation Plasmid (h) - sc-412527-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C17orf79 CRISPR Activation Plasmid (h2) - sc-412527-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C17orf79 Lentiviral Activation Particles (h) - sc-412527-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C17orf79 Lentiviral Activation Particles (h2) - sc-412527-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C17orf79 siRNA (h) - sc-94197 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

C17orf79 shRNA Plasmid (h) - sc-94197-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

C17orf79 shRNA (h) Lentiviral Particles - sc-94197-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU009221 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4485 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4485 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02311 from Sigma-Aldrich

Category miRNA

COPRS siRNA (Human) - CRJ0681 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

COPRS - MBS8213603 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human C17orf79 (NM_018405.3) - SHH249951 from Creative biogene

Category siRNA
Species Reactivities Human

COPRS shRNA Plasmid (Human) - CHJ0681 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

C17ORF79 miRNA 3'UTR clone - MiUTR3H-13972 from Creative biogene

Species Reactivities Human
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