Gene Symbol | ST8SIA4 |
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Entrez Gene | 7903 |
Alt Symbol | PST, PST1, SIAT8D, ST8SIA-IV |
Species | Human |
Gene Type | protein-coding |
Description | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
Other Description | CMP-N-acetylneuraminate-poly-alpha-2,8-sialyl transferase|CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase|SIAT8-D|ST8SiaIV|alpha-2,8-sialyltransferase 8D|polysialyltransferase-1|sialyltransferase 8 (alpha-2, 8-polysialytransferase) D|sialyltransferase 8D|sialyltransferase St8Sia IV|sialytransferase St8Sia IV |
Swissprots | Q92693 Q92187 A8KA07 Q8N1F4 G3V104 |
Accessions | CAN37586 CAS91698 EAW49104 EAW49105 Q92187 AA836260 AK292872 BAF85561 BC027866 AAH27866 BC040671 BC053657 AAH53657 BI858673 BM921020 DA862968 HQ448744 ADQ33222 L41680 AAC41775 XM_005272078 XP_005272135 XM_011543630 XP_011541932 NM_005668 NP_005659 NM_175052 NP_778222 |
Function | Catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid (PSA), which is present on the embryonic neural cell adhesion molecule (N-CAM), necessary for plasticity of neural cells. |
Subcellular Location | Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Tissue Specificity | Highly expressed in fetal brain, lung and kidney and in adult heart, spleen and thymus. Present to a lesser extent in adult brain, placenta, lung, large and small intestine and peripheral blood leukocytes. |
ST8Sia IV (H-70) - sc-68896 from Santa Cruz Biotechnology
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ST8Sia IV (E-13) - sc-109048 from Santa Cruz Biotechnology
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Anti-SIA8D antibody - ab103036 from Abcam
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Anti-SIA8D antibody - ab82967 from Abcam
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Anti-SIA8D antibody - ab155497 from Abcam
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Anti-SIA8D antibody - ab133921 from Abcam
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Anti-ST8SIA4 Antibody (aa193-222) - LS-C161534 from LifeSpan Bioscience
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Anti-ST8SIA4 Antibody (aa193-222, AP) - LS-C270465 from LifeSpan Bioscience
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Anti-ST8SIA4 Antibody (aa193-222, APC) - LS-C270467 from LifeSpan Bioscience
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Anti-ST8SIA4 Antibody (aa193-222, Biotin) - LS-C270468 from LifeSpan Bioscience
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Anti-ST8SIA4 Antibody (aa193-222, FITC) - LS-C270469 from LifeSpan Bioscience
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Anti-ST8SIA4 Antibody (aa193-222, Azide-free, HRP) - LS-C270470 from LifeSpan Bioscience
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Anti-ST8SIA4 Antibody (aa193-222, PE) - LS-C270471 from LifeSpan Bioscience
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Anti-ST8SIA4 Antibody (aa193-222) - LS-C325419 from LifeSpan Bioscience
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Anti-ST8SIA4 Antibody (C-Terminus) - LS-C151247 from LifeSpan Bioscience
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Anti-ST8SIA4 Antibody (clone 1H5) - LS-C198509 from LifeSpan Bioscience
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Anti-ST8SIA4 Antibody (aa180-229) - LS-C102313 from LifeSpan Bioscience
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ST8 alpha-2,8-Sialyltransferase 4/ST8SIA4 Antibody - NBP2-29951 from Novus Biologicals
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ST8 alpha-2,8-Sialyltransferase 4/ST8SIA4 Antibody - NBP1-79292 from Novus Biologicals
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ST8 alpha-2,8-Sialyltransferase 4/ST8SIA4 Antibody - NBP2-13393 from Novus Biologicals
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ST8 alpha-2,8-Sialyltransferase 4/ST8SIA4 Antibody - NBP2-20497 from Novus Biologicals
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ST8 alpha-2,8-Sialyltransferase 4/ST8SIA4 Antibody - NBP2-20496 from Novus Biologicals
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ST8 alpha-2,8-Sialyltransferase 4/ST8SIA4 Antibody (1H5) - H00007903-M03 from Novus Biologicals
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Monoclonal Anti-ST8SIA4 antibody produced in mouse - SAB1402975 from Sigma-Aldrich
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Anti-ST8SIA4 antibody produced in rabbit - SAB2102315 from Sigma-Aldrich
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