LGALS3

Gene Symbol	LGALS3
Entrez Gene	3958
Alt Symbol	CBP35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2
Species	Human
Gene Type	protein-coding
Description	lectin, galactoside-binding, soluble, 3
Other Description	35 kDa lectin|IgE-binding protein|MAC-2 antigen|carbohydrate-binding protein 35|galactose-specific lectin 3|galectin-3|laminin-binding protein|lectin L-29
Swissprots	B2RC38 P17931 Q96J47 Q6IBA7 Q16005
Accessions	AAB86584 BAC45249 CBX53892 EAW80658 EAW80660 P17931 AB006780 BAA22164 AB209391 BAD92628 AF266280 AAG44701 AK314929 BAG37435 BC001120 AAH01120 BC053667 AAH53667 BC068068 AAH68068 BC128253 BC128403 BG332134 BQ645629 BU681070 BX161455 CAD61918 BX641090 CAE46042 CD518618 CR456897 CAG33178 CR542097 CAG46894 DQ892594 ABM83520 EU176706 ABW03507 M35368 AAA88086 M36682 AAA36163 M57710 AAA35607 M64303 S59012 AAB26229 XM_011536759 XP_011535061 NM_001177388 NP_001170859 NM_002306 NP_002297 NR_003225
Function	Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. {ECO:0000250, ECO:0000269|PubMed:15181153, ECO:0000269|PubMed:19594635, ECO:0000269|PubMed:19616076}.
Subcellular Location	Cytoplasm. Nucleus. Secreted. Note=Secreted by a non-classical secretory pathway and associates with the cell surface.
Tissue Specificity	A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages. Expressed in fetal membranes. {ECO:0000269|PubMed:19497882}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-LGALS3-cDNA-Clone - DC07973 from Abgent, a WuXi AppTec company Prices $337.50 Sizes 10 µg Species Human Accession BC001120

LGALS3 - MBS1273962 from MyBioSource Prices $190.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC001120

LGALS3 - MBS1265837 from MyBioSource Prices $190.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC053667

Human LGALS3 cDNA clone(NM_001177388.1) - CDFH010331 from Creative Biomart Species Human Accession NM_001177388.1

Human LGALS3 ORF Clone(NM_001177388.1) - CDCR357029 from Creative Biomart Species Human Accession NM_001177388.1

Human LGALS3 ORF Clone(NM_001177388.1) - CDCR357030 from Creative Biomart Species Human Accession NM_001177388.1

Human LGALS3 ORF Clone(NM_001177388.1) - CDCL168609 from Creative Biomart Species Human Accession NM_001177388.1

Human LGALS3 transcript variant 1 Gene ORF cDNA clone in cloning vector - HG10289-G from Sino Biological Species Human

Human LGALS3 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG10289-ANG from Sino Biological Species Human

Human LGALS3 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10289-ACG from Sino Biological Species Human

Human LGALS3 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10289-ACR from Sino Biological Species Human

Human LGALS3 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG10289-ANR from Sino Biological Species Human

Human LGALS3 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-His tag - HG10289-NH from Sino Biological Species Human

Human LGALS3 transcript variant 1 Gene ORF cDNA clone expression plasmid - HG10289-UT from Sino Biological Species Human

Human LGALS3 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10289-CY from Sino Biological Species Human

Human LGALS3 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10289-NF from Sino Biological Species Human

Human LGALS3 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10289-NM from Sino Biological Species Human

Human LGALS3 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10289-CF from Sino Biological Species Human

Human LGALS3 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-His tag - HG10289-CH from Sino Biological Species Human

Human LGALS3 transcript variant 1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10289-NY from Sino Biological Species Human

Human LGALS3 transcript variant 1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10289-CM from Sino Biological Species Human

Human Galectin-3 ORF clone(NM_002306.3) - CDCL184359 from Creative biogene Species Human

Mouse LGALS3 ORF clone (NM_001177388.1) - CDCL126943 from Creative biogene Species Human

Human LGALS3 ORF Clone (BC001120) - CDCS409073 from Creative biogene Species Human Accession P17931

Human LGALS3 ORF Clone (BC053667) - CDCS409074 from Creative biogene Species Human Accession P17931

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