LGALS3

Gene Symbol	LGALS3
Entrez Gene	3958
Alt Symbol	CBP35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2
Species	Human
Gene Type	protein-coding
Description	lectin, galactoside-binding, soluble, 3
Other Description	35 kDa lectin|IgE-binding protein|MAC-2 antigen|carbohydrate-binding protein 35|galactose-specific lectin 3|galectin-3|laminin-binding protein|lectin L-29
Swissprots	B2RC38 P17931 Q96J47 Q6IBA7 Q16005
Accessions	AAB86584 BAC45249 CBX53892 EAW80658 EAW80660 P17931 AB006780 BAA22164 AB209391 BAD92628 AF266280 AAG44701 AK314929 BAG37435 BC001120 AAH01120 BC053667 AAH53667 BC068068 AAH68068 BC128253 BC128403 BG332134 BQ645629 BU681070 BX161455 CAD61918 BX641090 CAE46042 CD518618 CR456897 CAG33178 CR542097 CAG46894 DQ892594 ABM83520 EU176706 ABW03507 M35368 AAA88086 M36682 AAA36163 M57710 AAA35607 M64303 S59012 AAB26229 XM_011536759 XP_011535061 NM_001177388 NP_001170859 NM_002306 NP_002297 NR_003225
Function	Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. {ECO:0000250, ECO:0000269|PubMed:15181153, ECO:0000269|PubMed:19594635, ECO:0000269|PubMed:19616076}.
Subcellular Location	Cytoplasm. Nucleus. Secreted. Note=Secreted by a non-classical secretory pathway and associates with the cell surface.
Tissue Specificity	A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages. Expressed in fetal membranes. {ECO:0000269|PubMed:19497882}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Galectin 3 full length protein - ab179972 from Abcam Category Protein Prices $428.00 Sizes 200 µg Source E. coli Species Human

Active human Galectin 3 full length protein - ab78583 from Abcam Category Protein Prices $155.00, $1,089.00 Sizes 10 µg, 500 µg Source E. coli Species Human

Human Galectin 3 full length protein - ab89487 from Abcam Category Protein Source E. coli Species Human

Human Galectin 3 full length protein - ab50236 from Abcam Category Protein Source E. coli Species Human

Human Galectin 3 peptide - ab31706 from Abcam Category Peptide

Mouse Galectin 3 full length protein - ab137144 from Abcam Category Protein Source E. coli Species Mouse

LGALS2 / Galectin 2 Antibody Blocking Peptide - LS-E9754 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LGALS3 / Galectin 3 Antibody Blocking Peptide - LS-E1311 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LGALS3 / Galectin 3 Antibody Blocking Peptide - LS-E2651 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LGALS3 / Galectin 3 Antibody Blocking Peptide - LS-E19708 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LGALS3 / Galectin 3 Antibody Blocking Peptide - LS-E27628 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LGALS3 / Galectin 3 Antibody Blocking Peptide - LS-E6545 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Galectin-3 Protein - NBP2-34881 from Novus Biologicals Category Protein Prices $69.00, $169.00, $1,299.00 Sizes 10 µg, 50 µg, 1 mg Source E. coli Species Human

Galectin-3 Recombinant Protein - H00003958-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Galectin-3 Protein - NBP1-30277 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Species Human

Galectin-3 Recombinant Protein - P4391 from Novus Biologicals Category Protein Prices $549.00 Sizes 50 µg Species Human

Galectin-3 Protein - NBP1-99149 from Novus Biologicals Category Protein Species Human

Galectin-3 Protein - NBP1-99380 from Novus Biologicals Category Protein Prices $309.00 Sizes 50 µg Species Human

Recombinant Human Galectin-2 Protein - NBP1-48326 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E.coli Species Human

Galectin-2 Recombinant Protein - P3410 from Novus Biologicals Category Protein Prices $549.00 Sizes 100 µg Species Human

LGALS3-Antibody-C-term-Blocking-peptide - BP11938b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

LGALS3-Antibody-C-term-Blocking-peptide - BP13725b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Galectin 3 recombinant protein - GTX65161 from GeneTex Category Protein Prices $199.00 Sizes 10 μg Source E. coli Species Human

Galectin 3 recombinant protein - GTX65160 from GeneTex Category Protein Prices $249.00 Sizes 50 μg Source E. coli Species Human

Galectin 3 Recombinant Protein (Active) - GTX48403-PRO from GeneTex Category Protein Prices $299.00 Sizes 50 μg Source E. coli Species Human

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