ECSIT

Gene Symbol ECSIT
Entrez Gene 51295
Alt Symbol SITPEC
Species Human
Gene Type protein-coding
Description ECSIT signalling integrator
Other Description ECSIT homolog|evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial|likely ortholog of mouse signaling intermediate in Toll pathway evolutionarily conserved
Swissprots E9PAN9 Q9NYI1 Q96HQ7 Q9BQ95 K7EMM0
Accessions EAW84223 Q9BQ95 AF243044 AAF62100 AI336311 AI743680 AK314905 BC000193 AAH00193 BC005119 AAH05119 BC008279 AAH08279 BE791936 BU186092 CR457204 CAG33485 R46579 NM_001142464 NP_001135936 NM_001142465 NP_001135937 NM_001243204 NP_001230133 NM_016581 NP_057665
Function Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:17344420}. Nucleus {ECO:0000269|PubMed:17344420}. Mitochondrion {ECO:0000269|PubMed:17344420}.
Top Pathways MAPK signaling pathway

ECSIT (G-16) - sc-79470 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ECSIT (H-146) - sc-98508 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

ECSIT (V-14) - sc-79473 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ECSIT (T-25) - sc-133535 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
ECSIT (T-25): sc-133535. Western blot analysis of ECSIT expression in NIH/3T3 whole cell lysate.

Anti-ECSIT antibody - ab21288 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-ECSIT antibody (ab21288) at 0.5 µg/mlLane 2 : Anti-ECSIT antibody (ab21288) at 1 µg/mlLane 3 : Anti-ECSIT antibody (ab21288) at 2 µg/mlLane 1 : human heart lysateLane 2 : human heart lysateLane 3 : human heart lysate

Anti-ECSIT antibody - ab66380 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-ECSIT antibody (ab66380) at 1.25 µg/ml + NIH 3T3 lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-ECSIT antibody - C-terminal - ab199894 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-ECSIT antibody - C-terminal (ab199894) at 1/1000 dilutionLane 1 : HeLa total cell extractsLane 2 : Jurkat total cell extracts

Anti-ECSIT Antibody (C-Terminus) - LS-C6468 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ECSIT Antibody (aa396-425, Azide-free, HRP) - LS-C222313 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECSIT Antibody (aa396-425, APC) - LS-C222312 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECSIT Antibody (aa396-425, AP) - LS-C222311 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECSIT Antibody (aa396-425, Biotin) - LS-C222315 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECSIT Antibody (aa396-425, FITC) - LS-C222314 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECSIT Antibody (aa396-425, PE) - LS-C222316 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECSIT Antibody (aa395-425) - LS-C321016 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECSIT Antibody (aa241-290) - LS-C31040 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
NIH 3T3 Cell Lysate

Anti-ECSIT Antibody (aa51-100) - LS-C116059 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ECSIT antibody LS-C116059 Western blot of Mouse Heart lysate.

Anti-ECSIT Antibody (aa396-425) - LS-C167616 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Fluorescent confocal image of HeLa cell stained with ECSIT Antibody. HeLa cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with ECSIT primary antibody (1:25, 1 h at 37°C). For secondary antibody, Alexa Fluor 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37°C). Cytoplasmic actin was counterstained with Alexa Fluor 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37°C). Nuclei were counterstained with DAPI (blue) (10 ug/ml, 10 min). ECSIT immunoreactivity is localized to Cytoplasm and Nucleus significantly.

Anti-ECSIT Antibody (C-Terminus) IHC-plus™ - LS-B1351 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-ECSIT antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1351 concentration 5 ug/ml.

ECSIT Antibody - NBP1-91858 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ECSIT Antibody [NBP1-91858] - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.

ECSIT Antibody - NBP1-77838 from Novus Biologicals

Prices $369.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: ECSIT Antibody [NBP1-77838] - Shows detection of ECSIT in human heart whole cell lysate. The membrane was probed with the primary antibody diluted to 1:2000 (lane 1), 1:1000 (lane 2), and 1:500 (lane 3) respectively.

ECSIT Antibody - NBP1-76594 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: ECSIT Antibody [NBP1-76594] - Human heart cell lysates with ECSIT antibody at (A) 0.5, (B) 1, and (C) 2 ug/ml.

ECSIT Antibody (1B8) - H00051295-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1B8
Proximity Ligation Assay: ECSIT Antibody (1B8) [H00051295-M01] - Analysis of protein-protein interactions between SMURF1 and ECSIT. HeLa cells were stained with anti-SMURF1 rabbit purified polyclonal 1:1200 and anti-ECSIT mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).

Monoclonal Anti-SITPEC antibody produced in mouse - WH0051295M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1B8

Anti-ECSIT antibody produced in rabbit - PRS3377 from Sigma-Aldrich

Prices $347.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ECSIT: <B>Cat. No. PRS3377</B> Immunohistochemistry of ECSIT in mouse heart cells with ECSIT antibody at 2 μg/mL.
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