Gene Symbol | ECSIT |
---|---|
Entrez Gene | 51295 |
Alt Symbol | SITPEC |
Species | Human |
Gene Type | protein-coding |
Description | ECSIT signalling integrator |
Other Description | ECSIT homolog|evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial|likely ortholog of mouse signaling intermediate in Toll pathway evolutionarily conserved |
Swissprots | E9PAN9 Q9NYI1 Q96HQ7 Q9BQ95 K7EMM0 |
Accessions | EAW84223 Q9BQ95 AF243044 AAF62100 AI336311 AI743680 AK314905 BC000193 AAH00193 BC005119 AAH05119 BC008279 AAH08279 BE791936 BU186092 CR457204 CAG33485 R46579 NM_001142464 NP_001135936 NM_001142465 NP_001135937 NM_001243204 NP_001230133 NM_016581 NP_057665 |
Function | Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:17344420}. Nucleus {ECO:0000269|PubMed:17344420}. Mitochondrion {ECO:0000269|PubMed:17344420}. |
Top Pathways | MAPK signaling pathway |
Human ECSIT full length protein - ab132231 from Abcam
|
||||||||||
Human ECSIT peptide - ab39757 from Abcam
|
||||||||||
Human ECSIT protein fragment - ab132230 from Abcam
|
||||||||||
Human ECSIT protein fragment - ab134621 from Abcam
|
||||||||||
ECSIT Antibody Blocking Peptide - LS-E3655 from LifeSpan Bioscience
|
||||||||||
ECSIT Antibody Blocking Peptide - LS-E30087 from LifeSpan Bioscience
|
||||||||||
ECSIT Antibody Blocking Peptide - LS-E13331 from LifeSpan Bioscience
|
||||||||||
ECSIT Antibody Blocking Peptide - LS-E13332 from LifeSpan Bioscience
|
||||||||||
ECSIT Recombinant Protein - H00051295-P02 from Novus Biologicals
|
||||||||||
ECSIT Recombinant Protein - H00051295-P01 from Novus Biologicals
|
||||||||||
Recombinant Human ECSIT Protein - NBP2-23017 from Novus Biologicals
|
||||||||||
ECSIT Peptide - NBP1-76594PEP from Novus Biologicals
|
||||||||||
ECSIT-Antibody-C-term-Blocking-Peptide - BP14858b from Abgent, a WuXi AppTec company
|
||||||||||
ECSIT Peptide - GTX85081-PEP from GeneTex
|
||||||||||
Human ECSIT protein (His Tag) - orb138724 from Biorbyt
|
||||||||||
Human ECSIT protein - orb168265 from Biorbyt
|
||||||||||
ECSIT protein (His tag) - 80R-2497 from Fitzgerald
|
||||||||||
SITPEC Blocking Peptide - 33R-4726 from Fitzgerald
|
||||||||||
ECSIT (19-217, His-tag) - AR50569PU-N from Acris Antibodies
|
||||||||||
ECSIT (19-217, His-tag) - AR50569PU-S from Acris Antibodies
|
||||||||||
ECSIT - H00051295-P01-10 from Acris Antibodies
|
||||||||||
ECSIT - H00051295-P01-25 from Acris Antibodies
|
||||||||||
ECSIT - H00051295-P02 from Acris Antibodies
|
||||||||||
ECSIT - H00051295-P02-10 from Acris Antibodies
|
||||||||||
ECSIT - H00051295-P02-25 from Acris Antibodies
|