QPCT

Gene Symbol	QPCT
Entrez Gene	25797
Alt Symbol	GCT, QC, sQC
Species	Human
Gene Type	protein-coding
Description	glutaminyl-peptide cyclotransferase
Other Description	EC|glutaminyl cyclase|glutaminyl-tRNA cyclotransferase|glutamyl cyclase
Swissprots	Q53TR4 Q3KRG6 Q16769 Q16770
Accessions	AAY14804 EAX00392 EAX00393 EAX00394 EAX00395 EAX00396 EAX00397 Q16769 AB062487 BAB93512 AK290605 BAF83294 BC015460 BC020456 BC036721 AAH36721 BC047756 AAH47756 BF970452 BI755122 HQ448627 ADQ33105 X67731 CAA47961 X71125 CAA50438 NM_012413 NP_036545
Function	Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides. {ECO:0000269|PubMed:15063747, ECO:0000269|PubMed:18486145, ECO:0000269|PubMed:21288892}.
Subcellular Location	Secreted {ECO:0000269|PubMed:18486145}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

QPCT-Over-expression-Lysate - LY15614a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

QPCT 293T Cell Transient Overexpression Lysate(Denatured) - H00025797-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

QPCT overexpression lysate - LY415772 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

QPCT 293 Cell Lysate - 407413 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

Glutaminyl-peptide Cyclotransferase/QPCT Overexpression Lysate (Native) - NBL1-15029 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

QPCT Over-expression Lysate Product - GWB-5432CC from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Human Glutaminyl cyclase / QPCT Insect Cell Lysate (WB positive control) - 13752-H07BL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human Glutaminyl cyclase Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175233 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

Glutaminyl-peptide Cyclotransferase/QPCT Overexpression Lysate (Denatured) - H00025797-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Glutaminyl-peptide Cyclotransferase/QPCT Overexpression Lysate (Denatured) - H00025797-T03 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Glutaminyl-peptide Cyclotransferase/QPCT Overexpression Lysate (Denatured) - H00025797-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Panoply™ Human QPCT Knockdown Stable Cell Line - CSC-DC012794 from Creative biogene Category Cell Line Species Human

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