QPCT

Gene Symbol	QPCT
Entrez Gene	25797
Alt Symbol	GCT, QC, sQC
Species	Human
Gene Type	protein-coding
Description	glutaminyl-peptide cyclotransferase
Other Description	EC|glutaminyl cyclase|glutaminyl-tRNA cyclotransferase|glutamyl cyclase
Swissprots	Q53TR4 Q3KRG6 Q16769 Q16770
Accessions	AAY14804 EAX00392 EAX00393 EAX00394 EAX00395 EAX00396 EAX00397 Q16769 AB062487 BAB93512 AK290605 BAF83294 BC015460 BC020456 BC036721 AAH36721 BC047756 AAH47756 BF970452 BI755122 HQ448627 ADQ33105 X67731 CAA47961 X71125 CAA50438 NM_012413 NP_036545
Function	Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides. {ECO:0000269|PubMed:15063747, ECO:0000269|PubMed:18486145, ECO:0000269|PubMed:21288892}.
Subcellular Location	Secreted {ECO:0000269|PubMed:18486145}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

QPCT (E-17) - sc-162053 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

QPCT (H-41) - sc-368896 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

QPCT (L-14) - sc-162054 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-QPCT antibody - ab200437 from Abcam Host Rabbit Clonality Polyclonal

Anti-QPCT antibody - ab57038 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-QPCT antibody - C-terminal - ab173108 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-QPCT / QC Antibody (aa314-343, AP) - LS-C217059 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-QPCT / QC Antibody (aa314-343, APC) - LS-C217060 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-QPCT / QC Antibody (aa314-343, Biotin) - LS-C217063 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-QPCT / QC Antibody (aa314-343, FITC) - LS-C217064 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-QPCT / QC Antibody (aa314-343, Azide-free, HRP) - LS-C217065 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-QPCT / QC Antibody (aa314-343, PE) - LS-C217066 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-QPCT / QC Antibody (FITC) - LS-C317665 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-QPCT / QC Antibody (HRP) - LS-C317666 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-QPCT / QC Antibody (Biotin) - LS-C318926 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-QPCT / QC Antibody (aa314-343) - LS-C324449 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-QPCT / QC Antibody (aa216-265) - LS-C102320 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-QPCT / QC Antibody (aa315-343) - LS-C158775 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-QPCT / QC Antibody - LS-C334897 from LifeSpan Bioscience Prices $255.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-QPCT / QC Antibody - LS-C317668 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-QPCT / QC Antibody (clone 3G2) - LS-C134053 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 3G2

Glutaminyl-peptide Cyclotransferase/QPCT Antibody - AF6368 from Novus Biologicals Prices $99.00, $359.00 Sizes 25 µg, 100 µg Host Sheep Clonality Polyclonal

Glutaminyl-peptide Cyclotransferase/QPCT Antibody - NBP1-81838 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Glutaminyl-peptide Cyclotransferase/QPCT Antibody - NBP1-79295 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Glutaminyl-peptide Cyclotransferase/QPCT Antibody - H00025797-B01P from Novus Biologicals Prices $359.00 Sizes 50 µg Host Mouse Clonality Polyclonal

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