QPCT

Gene Symbol	QPCT
Entrez Gene	25797
Alt Symbol	GCT, QC, sQC
Species	Human
Gene Type	protein-coding
Description	glutaminyl-peptide cyclotransferase
Other Description	EC|glutaminyl cyclase|glutaminyl-tRNA cyclotransferase|glutamyl cyclase
Swissprots	Q53TR4 Q3KRG6 Q16769 Q16770
Accessions	AAY14804 EAX00392 EAX00393 EAX00394 EAX00395 EAX00396 EAX00397 Q16769 AB062487 BAB93512 AK290605 BAF83294 BC015460 BC020456 BC036721 AAH36721 BC047756 AAH47756 BF970452 BI755122 HQ448627 ADQ33105 X67731 CAA47961 X71125 CAA50438 NM_012413 NP_036545
Function	Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides. {ECO:0000269|PubMed:15063747, ECO:0000269|PubMed:18486145, ECO:0000269|PubMed:21288892}.
Subcellular Location	Secreted {ECO:0000269|PubMed:18486145}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-QPCT-cDNA-Clone - DC07705 from Abgent, a WuXi AppTec company Prices $487.35 Sizes 10 µg Species Human Accession BC047756

QPCT - MBS1268682 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC047756

Human QPCT cDNA clone(NM_012413.3) - CDFH015670 from Creative Biomart Species Human Accession NM_012413.3

Human QPCT ORF Clone(NM_012413.3) - CDCR296017 from Creative Biomart Species Human Accession NM_012413.3

Human QPCT ORF Clone(NM_012413.3) - CDCR296018 from Creative Biomart Species Human Accession NM_012413.3

Human Glutaminyl cyclase / QPCT Gene ORF cDNA clone in cloning vector - HG13752-G from Sino Biological Species Human

Human Glutaminyl cyclase / QPCT Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13752-NM from Sino Biological Species Human

Human Glutaminyl cyclase / QPCT Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13752-CF from Sino Biological Species Human

Human Glutaminyl cyclase / QPCT Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13752-CM from Sino Biological Species Human

Human Glutaminyl cyclase / QPCT Gene ORF cDNA clone expression plasmid, N-His tag - HG13752-NH from Sino Biological Species Human

Human Glutaminyl cyclase / QPCT Gene ORF cDNA clone expression plasmid, C-HA tag - HG13752-CY from Sino Biological Species Human

Human Glutaminyl cyclase / QPCT Gene ORF cDNA clone expression plasmid - HG13752-UT from Sino Biological Species Human

Human Glutaminyl cyclase / QPCT Gene ORF cDNA clone expression plasmid, C-His tag - HG13752-CH from Sino Biological Species Human

Human Glutaminyl cyclase / QPCT Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13752-ACG from Sino Biological Species Human

Human Glutaminyl cyclase / QPCT Gene ORF cDNA clone expression plasmid, N-HA tag - HG13752-NY from Sino Biological Species Human

Human Glutaminyl cyclase / QPCT Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13752-ACR from Sino Biological Species Human

Human Glutaminyl cyclase / QPCT Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13752-NF from Sino Biological Species Human

Human QPCT ORF Clone(NM_012413.3) - CDCR296017 from Creative biogene Species Human

Human QPCT ORF Clone (BC047756) - CDCS413327 from Creative biogene Species Human Accession Q16769

Human QPCT ORF clone (BC047756) - CDCB159729 from Creative biogene Species Human

Human QPCT cDNA Clone(NM_012413.3) - CDFH015670 from Creative biogene Species Human

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