QPCT

Gene Symbol QPCT
Entrez Gene 25797
Alt Symbol GCT, QC, sQC
Species Human
Gene Type protein-coding
Description glutaminyl-peptide cyclotransferase
Other Description EC|glutaminyl cyclase|glutaminyl-tRNA cyclotransferase|glutamyl cyclase
Swissprots Q53TR4 Q3KRG6 Q16769 Q16770
Accessions AAY14804 EAX00392 EAX00393 EAX00394 EAX00395 EAX00396 EAX00397 Q16769 AB062487 BAB93512 AK290605 BAF83294 BC015460 BC020456 BC036721 AAH36721 BC047756 AAH47756 BF970452 BI755122 HQ448627 ADQ33105 X67731 CAA47961 X71125 CAA50438 NM_012413 NP_036545
Function Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides. {ECO:0000269|PubMed:15063747, ECO:0000269|PubMed:18486145, ECO:0000269|PubMed:21288892}.
Subcellular Location Secreted {ECO:0000269|PubMed:18486145}.

QPCT CRISPR/Cas9 KO Plasmid (h) - sc-405768 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

QPCT HDR Plasmid (h) - sc-405768-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

QPCT Double Nickase Plasmid (h) - sc-405768-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

QPCT Double Nickase Plasmid (h2) - sc-405768-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

QPCT CRISPR Activation Plasmid (h) - sc-405768-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

QPCT CRISPR Activation Plasmid (h2) - sc-405768-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

QPCT Lentiviral Activation Particles (h) - sc-405768-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

QPCT Lentiviral Activation Particles (h2) - sc-405768-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

QPCT siRNA (h) - sc-94268 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

QPCT shRNA Plasmid (h) - sc-94268-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

QPCT shRNA (h) Lentiviral Particles - sc-94268-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU036301 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17784 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17784 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

QPCT siRNA (Human) - CRH8501 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Glutaminyl-peptide Cyclotransferase/QPCT RNAi - H00025797-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

QPCT - MBS8233172 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

QPCT CRISPR/Cas9 KO Plasmid (h2) - sc-405768-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

QPCT HDR Plasmid (h2) - sc-405768-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human QPCT (NM_012413.3) - SHH387592 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human QPCT(NM_012413.3) - SHR156660 from Creative biogene

Category siRNA
Species Reactivities Human

QPCT shRNA Plasmid (Human) - CHH8501 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

QPCT miRNA 3'UTR clone - MiUTR1H-08530 from Creative biogene

Species Reactivities Human
Search more