QPCT

Gene Symbol	QPCT
Entrez Gene	25797
Alt Symbol	GCT, QC, sQC
Species	Human
Gene Type	protein-coding
Description	glutaminyl-peptide cyclotransferase
Other Description	EC|glutaminyl cyclase|glutaminyl-tRNA cyclotransferase|glutamyl cyclase
Swissprots	Q53TR4 Q3KRG6 Q16769 Q16770
Accessions	AAY14804 EAX00392 EAX00393 EAX00394 EAX00395 EAX00396 EAX00397 Q16769 AB062487 BAB93512 AK290605 BAF83294 BC015460 BC020456 BC036721 AAH36721 BC047756 AAH47756 BF970452 BI755122 HQ448627 ADQ33105 X67731 CAA47961 X71125 CAA50438 NM_012413 NP_036545
Function	Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides. {ECO:0000269|PubMed:15063747, ECO:0000269|PubMed:18486145, ECO:0000269|PubMed:21288892}.
Subcellular Location	Secreted {ECO:0000269|PubMed:18486145}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human QPCT full length protein - ab161786 from Abcam Category Protein Source Wheat germ Species Human

Human QPCT protein fragment - ab161787 from Abcam Category Protein Source Wheat germ Species Human

QPCT / QC Antibody Blocking Peptide - LS-E5030 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Glutaminyl-peptide Cyclotransferase/QPCT Protein - H00025797-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Source Wheat Germ Species Human

Glutaminyl-peptide Cyclotransferase/QPCT Recombinant Protein - H00025797-P01 from Novus Biologicals Category Peptide Prices $319.00 Sizes 25 ug 10 ug Species Human

QPCT-Antibody-C-term-Blocking-Peptide - BP17434b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human QPCT, CF - 6368-ZN-010 from R&D Systems Category Protein Source Spodoptera frugiperda, Sf 21 (baculovirus)-derived, Ala33-Leu361, with an N-terminal human CD33 signal sequence and 6-His tag

Human QPCT protein (His Tag) - orb139562 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 10 μg, 20 μg Source Baculovirus-Insect Cells Species Human

Human QPCT protein - orb246421 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

QPCT Blocking Peptide - 33R-8755 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Glutamyl cyclase / QPCT - H00025797-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Glutamyl cyclase / QPCT - H00025797-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

QPCT fusion protein - ag13416 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human QPCT, His tagged - QPCT-8608H from Creative Biomart Category Protein Source Baculovirus-Insect Cells Species Human

Recombinant Glutaminyl Peptide Cyclotransferase (QPCT) - RPH274Hu01 from Uscn Life Science Inc. Category Peptide Source E.coli Species Human

Human Glutaminyl cyclase / QPCT Protein (His Tag) - 13752-H07B-10 from Sino Biological Category Protein Prices $178.00, $298.00 Sizes 10 µg, 20 µg Source Baculovirus-Insect Cells Species Human

Recombinant Glutaminyl Peptide Cyclotransferase (QPCT) - RPH274Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Glutaminyl-peptide cyclotransferase(QPCT) - CSB-YP019135HU CSB-BP019135HU CSB-MP019135HU from Cusabio Category Peptide Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant Human Glutaminyl-peptide cyclotransferase - CSB-EP019135HU from Cusabio Category Peptide Source E.coli Species Human

QPCT, 29-361aa, Human, His tag, Baculovirus - ATGP3153 from ATGen Category Protein Prices $80.00, $240.00, $960.00 Sizes 10 µg, 50 µg, 250 µg Species Human

QPCT protein - 80R-4298 from Fitzgerald Category Protein Prices $275.00 Sizes 50 µg Source Insect cells

Recombinant Human QPCT Protein, CF - 6368-ZN from R&D Systems Category Protein Prices $329.00 Sizes 10 µg Source Spodoptera frugiperda , Sf 21 (baculovirus)-derived Ala33-Leu361, with an N-terminal human CD33 signal sequence and 6-His tag Species Human

Glutamyl cyclase / QPCT - TP308388 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Human Glutaminyl cyclase / QPCT Protein (His tag) - PKSH030564 from Elabscience Category Protein Source Baculoviru Species Human

Recombinant Human QPCT protein, His-tagged - QPCT-36H from Creative Biomart Category Protein Source Insect cell Species Human

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