DEDD

Gene Symbol	DEDD
Entrez Gene	9191
Alt Symbol	CASP8IP1, DEDD1, DEFT, FLDED1, KE05
Species	Human
Gene Type	protein-coding
Description	death effector domain containing
Other Description	DEDPro1|FLDED-1|death effector domain-containing protein|death effector domain-containing testicular molecule
Swissprots	O60737 D3DVF5 O75618
Accessions	EAW52648 EAW52649 EAW52650 EAW52651 EAW52652 EAW52653 O75618 AF043733 AAC80280 AF064605 AAC17110 AF083236 AAC33105 AF100341 AAD16414 AJ010973 CAA09445 AK001497 AK022531 BAG51086 AK296629 BAG59233 BC013910 AAH13910 BC016724 AAH16724 BG565440 CR536556 CAG38793 JF432647 ADZ15864 XM_005245597 XP_005245654 XM_005245598 XP_005245655 XM_005245599 XP_005245656 XM_005245600 XP_005245657 NM_001039711 NP_001034800 NM_001039712 NP_001034801 NM_032998 NP_127491 NM_004216
Function	A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm. Nucleus, nucleolus {ECO:0000250}. Note=Translocated to the nucleus during CD95-mediated apoptosis where it is localized in the nucleoli (By similarity). Following apoptosis induction, the mono and/or diubiquitination form increases and forms filamentous structures that colocalize with KRT8 and KRT18 intermediate filament network in simple epithelial cells. {ECO:0000250}.
Tissue Specificity	Widely expressed with highest levels in testis. {ECO:0000269|PubMed:9832420}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DEDD full length protein - ab140059 from Abcam Category Protein Source E. coli Species Human

DEDD Antibody Blocking Peptide - LS-E5975 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DEDD Partial Recombinant Protein - H00009191-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

DEDD Recombinant Protein - H00009191-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 2 µg Species Human

Recombinant Human DEDD Protein - NBP2-22990 from Novus Biologicals Category Protein Prices $349.00 Sizes 50 µg Source E.coli Species Human

DEDD-Antibody-Center-Blocking-Peptide - BP18537c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human DEDD protein - orb168205 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

DEDD protein (His tag) - 80R-2649 from Fitzgerald Category Protein Prices $365.00 Sizes 50 µg Source E.coli

DEDD (1-318, His-tag) - AR50769PU-N from Acris Antibodies Category Protein Prices $1,010.00 Sizes 250 µg Source E. coli Species Human

DEDD (1-318, His-tag) - AR50769PU-S from Acris Antibodies Category Protein Prices $410.00 Sizes 50 µg Source E. coli Species Human

DEDD - H00009191-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

DEDD - H00009191-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

DEDD - H00009191-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

DEDD - H00009191-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

DEDD, 1-318aa Human, His tag, E.coli - 01-P1945 from ARP American Research Products Category Protein Prices $179.00, $449.00, $1,089.00 Sizes 10 µg, 50 µg, 250 µg Species Human

DEDD fusion protein - ag1195 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

DEDD Human - PRPS-1356 from NeoScientific Category Protein Prices $65.00, $169.00, $6,760.00 Sizes 2 µg, 10 µg, 1 mg Source Escherichia Coli. Species Human

DEDD, 1-318aa Human, His tag, E.coli - GWB-PPST33 from Genway Biotech Category Protein Prices $400.00, $1,200.00 Sizes 50 μg, 250 μg Source E.coli Species Human

Recombinant Human Death effector domain-containing protein(DEDD) - CSB-YP006648HU CSB-EP006648HU CSB-BP006648HU CSB-MP006648HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

DEDD, 1-318aa, Human, His tag, E.coli (Denatured) - ATGP1945 from ATGen Category Protein Prices $105.00, $320.00, $960.00 Sizes 10 µg, 50 µg, 250 µg Species Human

DEDD (full length, N-term HIS tag, transcript variant 1) - TP760594 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

DEDD (full length, N-term HIS tag, transcript variant 4) - TP760627 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

Death Effector Domain Containing Protein (Recombinant) - abx262579 from Abbexa Category Protein

DEDD Peptide, Human - M34GP04177H from Creative Peptides Category Peptide Source Synthetic. Species Human

DEDD - PAT-81945-1 from Nordic BioSite Category Protein Species Human

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