CPB2

Gene Symbol CPB2
Entrez Gene 1361
Alt Symbol CPU, PCPB, TAFI
Species Human
Gene Type protein-coding
Description carboxypeptidase B2 (plasma)
Other Description carboxypeptidase B-like protein|carboxypeptidase B2|carboxypeptidase B2 (plasma, carboxypeptidase U)|carboxypeptidase R|thrombin-activable fibrinolysis inhibitor|thrombin-activatable fibrinolysis inhibitor
Swissprots Q5T9K1 Q96IY4 Q15114 A8K464 Q5T9K2 Q9P2Y6
Accessions AAT97987 EAX08754 EAX08755 Q96IY4 AA700377 AB011969 BAA90475 AK290829 BAF83518 AU100156 AV719308 BC007057 AAH07057 BT006936 AAP35582 DQ890567 ABM92184 EU176478 ABW03279 M75106 AAA60042 NM_001278541 NP_001265470 NM_001872 NP_001863 NM_016413
Function Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down- regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. {ECO:0000269|PubMed:10574983}.
Subcellular Location Secreted.
Tissue Specificity Plasma; synthesized in the liver.
Top Pathways Complement and coagulation cascades, Protein digestion and absorption, Pancreatic secretion

TAFI (H-58) - sc-67300 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TAFI (H-58): sc-67300. Western blot analysis of TAFI expression in human PBL whole cell lysate.

TAFI (A-14) - sc-67867 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TAFI (C-20) - sc-67868 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TAFI (K-15) - sc-67870 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TAFI (16C5) - sc-59709 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
TAFI (16C5): sc-59709. Western blot analysis of TAFI derived from human plasma.

TAFI (19E2) - sc-52241 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
TAFI (19E2): sc-52241. Western blot analysis of TAFI derived from human plasma.

TAFI (13H4) - sc-59708 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
TAFI (13H4): sc-59708. Western blot analysis of TAFI expression in human platelet extract.

Anti-Carboxypeptidase B2 antibody [13D5] - ab14756 from Abcam

Prices $370.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 13D5
Titration curves of carboxypeptidase B2 in plasma using antibody pair; capture ab14756, 200ng/well and HRPconjugated antibody ab14757. Incubated at room temperature.

Anti-Carboxypeptidase B2 antibody [13H4] (HRP) - ab14757 from Abcam

Prices $370.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 13H4
Titration curves of carboxypeptidase B2 in plasma using antibody pair; capture ab14756, 200ng/well and HRPconjugated antibody ab14757. Incubated at room temperature.

Anti-Carboxypeptidase B2 antibody [19E2] (HRP) - ab14767 from Abcam

Prices $370.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 19E2

Anti-Carboxypeptidase B2 antibody [EPR7858] - ab133679 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7858
All lanes : Anti-Carboxypeptidase B2 antibody [EPR7858] (ab133679) at 1/1000 dilutionLane 1 : Human platelet lysateLane 2 : Human plasma lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP conjugated antibody at 1/2000 dilution

Anti-Carboxypeptidase B2 antibody - ab83809 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Carboxypeptidase B2 antibody (ab83809) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal heart lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Carboxypeptidase B2 antibody - ab78445 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Carboxypeptidase B2 antibody (ab78445) at 1 µg/ml + Liver (Human) Tissue Lysate - adult normal tissue (ab29889) at 10 µgSecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Carboxypeptidase B2 antibody - ab136058 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Carboxypeptidase B2 antibody (ab136058) at 1/500 dilution + K562 cell lysates at 30 µg

Anti-CPB2 / TAFI Antibody - LS-C18009 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CPB2 / TAFI Antibody - LS-C18010 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CPB2 / TAFI Antibody - LS-C18011 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CPB2 / TAFI Antibody - LS-C18012 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CPB2 / TAFI Antibody - LS-C18013 from LifeSpan Bioscience

Host Sheep
Clonality Polyclonal

Anti-CPB2 / TAFI Antibody - LS-C18014 from LifeSpan Bioscience

Host Sheep
Clonality Polyclonal

Anti-CPB2 / TAFI Antibody (HRP) - LS-C18015 from LifeSpan Bioscience

Host Sheep
Clonality Polyclonal

Anti-CPB2 / TAFI Antibody - LS-C18023 from LifeSpan Bioscience

Host Sheep
Clonality Polyclonal

Anti-CPB2 / TAFI Antibody - LS-C39468 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CPB2 / TAFI Antibody (clone 15A10) - LS-C52482 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 15A10

Anti-CPB2 / TAFI Antibody (clone 16C5) - LS-C52484 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 16C5
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