CPB2

Gene Symbol	CPB2
Entrez Gene	1361
Alt Symbol	CPU, PCPB, TAFI
Species	Human
Gene Type	protein-coding
Description	carboxypeptidase B2 (plasma)
Other Description	carboxypeptidase B-like protein|carboxypeptidase B2|carboxypeptidase B2 (plasma, carboxypeptidase U)|carboxypeptidase R|thrombin-activable fibrinolysis inhibitor|thrombin-activatable fibrinolysis inhibitor
Swissprots	Q5T9K1 Q96IY4 Q15114 A8K464 Q5T9K2 Q9P2Y6
Accessions	AAT97987 EAX08754 EAX08755 Q96IY4 AA700377 AB011969 BAA90475 AK290829 BAF83518 AU100156 AV719308 BC007057 AAH07057 BT006936 AAP35582 DQ890567 ABM92184 EU176478 ABW03279 M75106 AAA60042 NM_001278541 NP_001265470 NM_001872 NP_001863 NM_016413
Function	Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down- regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. {ECO:0000269|PubMed:10574983}.
Subcellular Location	Secreted.
Tissue Specificity	Plasma; synthesized in the liver.
Top Pathways	Complement and coagulation cascades, Protein digestion and absorption, Pancreatic secretion

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CPB2 / TAFI ELISA Kit (Sandwich ELISA) - LS-F4338 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 0.137 ng/ml Range 0.313-20 ng/ml

Rat CPB2 / TAFI ELISA Kit (Sandwich ELISA) - LS-F4339 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.33 ng/ml Range 0.313-20 ng/ml

Mouse CPB2 / TAFI ELISA Kit (Sandwich ELISA) - LS-F4340 from LifeSpan Bioscience Category ELISA Kit Prices $670.00 Sizes 1 plate Sensitivity 0.128 ng/ml Range 0.313-20 ng/ml

Human CPB2 / TAFI ELISA Kit (Sandwich ELISA) - LS-F11042 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 3.12 ng/ml Range 0.313-20 ng/ml

Carboxypeptidase B2, CPB2, Human, ELISA Kit - E0615h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 3.12-200 ng/mL

Thrombin Activatable Fibrinolysis Inhibitor, TAFI, Human, ELISA Kit - E-EL-H2107 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 3 Range 5-320ng/mL

Thrombin Activatable Fibrinolysis Inhibitor (TAFI), Human, ELISA Kit - SEA615Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 0.67ng/mL Range 1.56-100ng/mL

Thrombin activatable fibrinolysis inhibitor, TAFI, Human, ELISA Kit - CSB-E08778h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Thrombin activatable fibrinolysis inhibitor, TAFI, Mouse, ELISA Kit - E-EL-M1135 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.469 Range 0.781-50ng/mL

Thrombin Activatable Fibrinolysis Inhibitor, TAFI, Rat, ELISA Kit - E-EL-R0955 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.938 Range 1.563-100ng/mL

Thrombin Activatable Fibrinolysis Inhibitor, TAFI, Rabbit, ELISA Kit - E-EL-RB0836 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Thrombin Activatable Fibrinolysis Inhibitor, TAFI, Chicken, ELISA Kit - E-EL-Ch2178 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Thrombin Activatable Fibrinolysis Inhibitor, TAFI, Porcine, ELISA Kit - E-EL-P0204 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Thrombin Activatable Fibrinolysis Inhibitor, TAFI, Guinea Pig, ELISA Kit - E-EL-GP1039 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Thrombin Activatable Fibrinolysis Inhibitor, TAFI, Monkey, ELISA Kit - E-EL-MK2168 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human TAFI ELISA Kit - HT0092 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine TAFI ELISA Kit - AT0092 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

ELISA Kit for Thrombin Activatable Fibrinolysis Inhibitor (TAFI) - SEA615Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.137ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for Thrombin Activatable Fibrinolysis Inhibitor (TAFI) - SEA615Mu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.32ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA’s were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

ELISA Kit for Thrombin Activatable Fibrinolysis Inhibitor (TAFI) - SEA615Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.33ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA’s were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

Human TAFI(Thrombin Activatable Fibrinolysis Inhibitor) ELISA Kit - E-EL-H2107 from Elabscience Category ELISA Kit Sensitivity 3.00 ng/mL Range 5.00—320 ng/mL

Human TAFI (Thrombin Activatable Fibrinolysis Inhibitor) CLIA Kit - E-CL-H1264 from Elabscience Category CLIA Kit Sensitivity 0.56 ng/mL Range Average Recovery (%)

carboxypeptidase B2 (plasma) , ELISA Kit - MBS703133 from MyBioSource Category ELISA Kit Prices $250.00, $960.00, $2,890.00, $5,465.00 Sizes 24 -strip-wells (Limit 1), 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human TAFI is typically less than 0.78 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 3.12 ng/ml -200 ng/ml.

Human Thrombin activatable fibrinolysis inhibitor,TAFI ELISA Kit - CSB-E08778h from Cusabio Category ELISA Kit Sensitivity 7.81 ng/ml Range 31.25 ng/ml-2000 ng/ml

Human Thrombin Activatable Fibrinolysis Inhibitor ELISA - E01T0085 from BlueGene Biotech Category ELISA Kit Sensitivity 1.0 ng/mL

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