CPB2

Gene Symbol	CPB2
Entrez Gene	1361
Alt Symbol	CPU, PCPB, TAFI
Species	Human
Gene Type	protein-coding
Description	carboxypeptidase B2 (plasma)
Other Description	carboxypeptidase B-like protein|carboxypeptidase B2|carboxypeptidase B2 (plasma, carboxypeptidase U)|carboxypeptidase R|thrombin-activable fibrinolysis inhibitor|thrombin-activatable fibrinolysis inhibitor
Swissprots	Q5T9K1 Q96IY4 Q15114 A8K464 Q5T9K2 Q9P2Y6
Accessions	AAT97987 EAX08754 EAX08755 Q96IY4 AA700377 AB011969 BAA90475 AK290829 BAF83518 AU100156 AV719308 BC007057 AAH07057 BT006936 AAP35582 DQ890567 ABM92184 EU176478 ABW03279 M75106 AAA60042 NM_001278541 NP_001265470 NM_001872 NP_001863 NM_016413
Function	Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down- regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. {ECO:0000269|PubMed:10574983}.
Subcellular Location	Secreted.
Tissue Specificity	Plasma; synthesized in the liver.
Top Pathways	Complement and coagulation cascades, Protein digestion and absorption, Pancreatic secretion

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

TAFI CRISPR/Cas9 KO Plasmid (h) - sc-416317 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

TAFI HDR Plasmid (h) - sc-416317-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

TAFI Double Nickase Plasmid (h) - sc-416317-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

TAFI Double Nickase Plasmid (h2) - sc-416317-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

TAFI CRISPR Activation Plasmid (h) - sc-416317-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

TAFI CRISPR Activation Plasmid (h2) - sc-416317-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

TAFI Lentiviral Activation Particles (h) - sc-416317-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

TAFI Lentiviral Activation Particles (h2) - sc-416317-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

TAFI siRNA (h) - sc-63098 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

TAFI shRNA Plasmid (h) - sc-63098-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

TAFI shRNA (h) Lentiviral Particles - sc-63098-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU097601 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6496 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6496 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03665 from Sigma-Aldrich Category miRNA

CPB2 siRNA (Human) - CRH0951 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

Carboxypeptidase B2/CPB2 RNAi - H00001361-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

Carboxypeptidase B2/CPB2 RNAi - H00001361-R02 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

CPB2 - MBS8200317 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human CPB2 (NM_001872.3) - SHH268573 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human CPB2(NM_001872.3) - SHG195305 from Creative biogene Category siRNA Species Reactivities Human

Human CPB2 siRNA - orb261453 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

CPB2 shRNA Plasmid (Human) - CHH0951 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

CPB2 miRNA 3'UTR clone - MiUTR1H-02386 from Creative biogene Species Reactivities Human

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