Gene Symbol | NEK9 |
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Entrez Gene | 91754 |
Alt Symbol | NERCC, NERCC1, Nek8 |
Species | Human |
Gene Type | protein-coding |
Description | NIMA-related kinase 9 |
Other Description | NIMA (never in mitosis gene a)- related kinase 9|NIMA-related kinase Nek8|nercc1 kinase|never in mitosis A-related kinase 9|nimA-related kinase 8|nimA-related protein kinase 9|serine/threonine-protein kinase Nek9 |
Swissprots | Q8NCN0 Q8TD19 Q9Y6S5 Q9UPI4 Q8TCY4 Q52LK6 Q9Y6S6 Q9Y6S4 |
Accessions | AAD31936 AAD31938 AAD31939 AAD31940 EAW81220 EAW81221 EAW81222 Q8TD19 AB082526 BAC02704 AK128693 BAG54712 AL117502 AL832633 AL833036 AY048580 AAL05428 AY080896 AAL87410 BC001714 AAH01714 BC009336 AAH09336 BC093881 AAH93881 BC112101 AAI12102 BM976692 DB455229 XM_005268208 XP_005268265 XM_005268209 XP_005268266 NM_033116 NP_149107 |
Function | Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression. Phosphorylates NEK6 and NEK7 and stimulates their activity by releasing the autoinhibitory functions of Tyr-108 and Tyr-97 respectively. {ECO:0000269|PubMed:12840024, ECO:0000269|PubMed:14660563, ECO:0000269|PubMed:19941817}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:14660563}. Nucleus {ECO:0000269|PubMed:14660563}. |
Tissue Specificity | Most abundant in heart, liver, kidney and testis. Also expressed in smooth muscle cells and fibroblasts. |
Mouse/Human/Rat Phospho-NEK9 (Thr210) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1420 from LifeSpan Bioscience
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Mouse/Human/Rat NEK9 ELISA Kit (Cell-Based ELISA) - LS-F2181 from LifeSpan Bioscience
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Rabbit anti-NEK9 Antibody, Affinity Purified - PLA0169 from Sigma-Aldrich
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NEK9 (Human) IP-WB Antibody Pair - H00091754-PW1 from Acris Antibodies
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NEK9 Colorimetric Cell-Based ELISA Kit - CB5483 from Assay Biotechnology
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NEK9 (Phospho-Thr210) Colorimetric Cell-Based ELISA Kit - CBP1452 from Assay Biotechnology
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NIMA (never in mitosis gene a) - related kinase 9, ELISA Kit - MBS9336477 from MyBioSource
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NEK9 ELISA Kit - DEIA-XYA1309 from Creative Diagnostics
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NEK9 (Phospho-Thr210) ELISA Kit - DEIA-XYA1310 from Creative Diagnostics
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Human NEK9 ELISA Kit - E026576 from Biobool
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NEK9 Colorimetric Cell-Based ELISA Kit - EKA50416 from Biomatik
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