MSL1

Gene Symbol MSL1
Entrez Gene 339287
Alt Symbol MSL-1, hMSL1
Species Human
Gene Type protein-coding
Description male-specific lethal 1 homolog (Drosophila)
Other Description MSL1-like 1|male-specific lethal 1 homolog|male-specific lethal 1-like 1|male-specific lethal-1 homolog 1
Swissprots Q69Z03 Q0VF46 Q68DK7
Accessions Q68DK7 AK055378 AK124185 AK125654 BAG54229 AK297619 BAG59995 AL049450 CAH10734 BC039449 BC118997 AAI18998 BC122543 AAI22544 BX647188 CR749360 CAH18213 EU831932 ACE87373 EU832027 ACE86689 R23466 XM_005257298 XP_005257355 XM_005257299 XP_005257356 XM_011524740 XP_011523042 NM_001012241 NP_001012241
Function Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at 'Lys-16' (H4K16ac) which is implicated in the formation of higher-order chromatin structure. Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at 'Lys-34' (H2BK34Ub). This modification in turn stimulates histone H3 methylation at 'Lys-4' (H3K4me) and 'Lys-79' (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1. In the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together for enzymatic activity regulation. {ECO:0000269|PubMed:16227571, ECO:0000269|PubMed:21726816, ECO:0000269|PubMed:22547026}.
Subcellular Location Nucleus {ECO:0000269|PubMed:15561718}.

MSL-1 (C-16) - sc-168659 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MSL-1 (C-16): sc-168659. Western blot analysis of MSL-1 expression in non-transfected: sc-117752 (A) and human MSL-1 transfected: sc-177568 (B) 293T whole cell lysates.

MSL-1 (Q-19) - sc-168661 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MSL-1 (Q-19): sc-168661. Western blot analysis of MSL-1 expression in non-transfected: sc-117752 (A) and human MSL-1 transfected: sc-177568 (B) 293T whole cell lysates.

Anti-MSL1 antibody - ab121718 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab121718 at 1/400 dilution staining MSL1v1 in Paraffin-embedded Human Prostate tissue by Immunohistochemistry.

Anti-MSL1 antibody - ab121762 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab121762 at 1/100 dilution staining MSL1v1 in Paraffin-emebedded Human cerebellum tissue by Immunohistochemistry.

Anti-MSL1 antibody - ab123272 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-MSL1 antibody (ab123272) at 1/100 dilution + HeLa cell lysate at 35 µg

Anti-MSL1 Antibody (aa339-367, AP) - LS-C237818 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MSL1 Antibody (aa339-367, Biotin) - LS-C237819 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MSL1 Antibody (aa339-367, APC) - LS-C237820 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MSL1 Antibody (aa339-367, FITC) - LS-C237821 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MSL1 Antibody (aa339-367, Azide-free, HRP) - LS-C248856 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MSL1 Antibody (aa338-367) - LS-C323132 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MSL1 Antibody (aa339-367, PE) - LS-C237822 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MSL1 Antibody (aa118-167) - LS-C151707 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MSL1 antibody Western Blot of 721_B.

Anti-MSL1 Antibody (aa339-367) - LS-C164650 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
MSL1 Antibody western blot of HeLa cell line lysates (35 ug/lane). The MSL1 antibody detected the MSL1 protein (arrow).

MSL1 Antibody - NBP1-90506 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: MSL1 Antibody [NBP1-90506] - Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.

MSL1 Antibody - NBP1-90505 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: MSL1 Antibody [NBP1-90505] - Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.

ANTI-MSL1 (CENTER) antibody produced in rabbit - SAB1306806 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-MSL1 (Center): <B>Cat. No. SAB1306806</B>: MSL1 Antibody (Center) western blot analysis in HeLa cell line lysates (35 μg/lane).

Anti-MSL1 antibody produced in rabbit - HPA022800 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MSL1: <B>Cat. No. HPA022800</B>: Immunohistochemical staining of human prostate shows strong cytoplasmic positivity in glandular cells.

Anti-MSL1 antibody produced in rabbit - HPA023567 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MSL1: <B>Cat. No. HPA023567</B>: Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in purkinje cells.

MSL1 antibody - middle region (ARP64394_P050) - ARP64394_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

MSL1-Antibody-Center - AP14386c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
MSL1 Antibody (Center) (Cat. #AP14386c) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the MSL1 antibody detected the MSL1 protein (arrow).

MSL1 Antibody - middle region (OAAB10684) - OAAB10684 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

MSL1 Antibody - abx028019 from Abbexa

Host Rabbit
Clonality Polyclonal

MSL1 antibody - 24373-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
HeLa cells were subjected to SDS PAGE followed by western blot with 24373-1-AP( MSL1 Antibody) at dilution of 1:600

MSL1 antibody - H00339287-B01P from Acris Antibodies

Prices $1,530.00
Sizes 500 µg
Host Mouse
Clonality Polyclonal
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