MSL1

Gene Symbol	MSL1
Entrez Gene	339287
Alt Symbol	MSL-1, hMSL1
Species	Human
Gene Type	protein-coding
Description	male-specific lethal 1 homolog (Drosophila)
Other Description	MSL1-like 1|male-specific lethal 1 homolog|male-specific lethal 1-like 1|male-specific lethal-1 homolog 1
Swissprots	Q69Z03 Q0VF46 Q68DK7
Accessions	Q68DK7 AK055378 AK124185 AK125654 BAG54229 AK297619 BAG59995 AL049450 CAH10734 BC039449 BC118997 AAI18998 BC122543 AAI22544 BX647188 CR749360 CAH18213 EU831932 ACE87373 EU832027 ACE86689 R23466 XM_005257298 XP_005257355 XM_005257299 XP_005257356 XM_011524740 XP_011523042 NM_001012241 NP_001012241
Function	Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at 'Lys-16' (H4K16ac) which is implicated in the formation of higher-order chromatin structure. Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at 'Lys-34' (H2BK34Ub). This modification in turn stimulates histone H3 methylation at 'Lys-4' (H3K4me) and 'Lys-79' (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1. In the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together for enzymatic activity regulation. {ECO:0000269|PubMed:16227571, ECO:0000269|PubMed:21726816, ECO:0000269|PubMed:22547026}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:15561718}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MSL1 Antibody Blocking Peptide - LS-E3237 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MSL1 Antibody Blocking Peptide - LS-E23479 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MSL1-Antibody-Center-Blocking-Peptide - BP14386c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MSL1 fusion protein - ag18024 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

MSL1 fusion protein - ag19174 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human Male-specific lethal 1 homolog(MSL1) - CSB-YP731563HU CSB-EP731563HU CSB-BP731563HU CSB-MP731563HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

MSL1 Recombinant Protein Antigen - NBP1-90506PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MSL1 Recombinant Protein Antigen - NBP1-90505PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MSL1 Peptide, Human - M34GP09826H from Creative Peptides Category Peptide Source Synthetic. Species Human

Male-specific lethal 1 homolog (MSL1), Recombinant Protein - MBS1467938 from MyBioSource Category Protein Prices $1,410.00, $1,410.00, $1,635.00, $1,635.00, $2,380.00, $2,380.00, $2,820.00, $2,820.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Search more