DR1

Gene Symbol	DR1
Entrez Gene	1810
Alt Symbol	NC2, NC2-BETA
Species	Human
Gene Type	protein-coding
Description	down-regulator of transcription 1, TBP-binding (negative cofactor 2)
Other Description	TATA-binding protein-associated phosphoprotein|negative cofactor 2-beta|protein Dr1
Swissprots	Q01658
Accessions	EAW73072 EAW73073 EAW73074 EAW73075 EAW73076 Q01658 AK057541 BAG51931 AK223442 BAD97162 AK311288 AL137673 AL833729 CAH56250 BC002809 AAH02809 BC035507 AAH35507 BC068553 AAH68553 BT006972 AAP35618 M97388 AAA58442 NM_001938 NP_001929
Function	The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. {ECO:0000269|PubMed:19103755, ECO:0000269|PubMed:8670811}.
Subcellular Location	Nucleus.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DR1 full length protein - ab172153 from Abcam Category Protein Source E. coli Species Human

Human DR1 full length protein - ab178491 from Abcam Category Protein Source Saccharomyces cerevisiae Species Human

Human DR1 full length protein - ab98246 from Abcam Category Protein Source E. coli Species Human

Human DR1 full length protein - ab81795 from Abcam Category Protein Source E. coli Species Human

Human DR1 full length protein - ab84121 from Abcam Category Protein Source E. coli Species Human

DR1 / NC2 Antibody Blocking Peptide - LS-E5338 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DR1 / NC2 Antibody Blocking Peptide - LS-E10916 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DR1 / NC2 Antibody Blocking Peptide - LS-E13663 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

DR1 Partial Recombinant Protein - H00001810-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

DR1 Recombinant Protein - H00001810-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human DR1 Protein - NBP1-45319 from Novus Biologicals Category Protein Prices $299.00, $729.00 Sizes 100 µg, 500 µg Source E.coli Species Human

DR1-Antibody-Center-Blocking-Peptide - BP17826c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DR1 Protein (OPPA02418) - OPPA02418 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human DR1 protein - orb81072 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 25 μg Species Human

DR1 protein (His tag) - 80R-1431 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

DR1 / NC2-beta (1-176, His-tag) - AR09607PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

DR1 / NC2-beta (1-176, His-tag) - AR09607PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

DR1 / NC2-beta - H00001810-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

DR1 / NC2-beta - H00001810-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

DR1 / NC2-beta - H00001810-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

DR1 / NC2-beta - H00001810-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

DR1, 1-176aa, Human, His tag, E.coli - 01-1909-1 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

Protein Dr1, DR1, Human, Recombinant - 19-CE32 from ARP American Research Products Category Protein Prices $169.00 Sizes 10 µg Source E. coli Species Human

DR1 fusion protein - Ag0664 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

DR1 Human - PRPS-549 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 25 µg, 1 mg Source Escherichia Coli. Species Human

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