DR1

Gene Symbol DR1
Entrez Gene 1810
Alt Symbol NC2, NC2-BETA
Species Human
Gene Type protein-coding
Description down-regulator of transcription 1, TBP-binding (negative cofactor 2)
Other Description TATA-binding protein-associated phosphoprotein|negative cofactor 2-beta|protein Dr1
Swissprots Q01658
Accessions EAW73072 EAW73073 EAW73074 EAW73075 EAW73076 Q01658 AK057541 BAG51931 AK223442 BAD97162 AK311288 AL137673 AL833729 CAH56250 BC002809 AAH02809 BC035507 AAH35507 BC068553 AAH68553 BT006972 AAP35618 M97388 AAA58442 NM_001938 NP_001929
Function The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. {ECO:0000269|PubMed:19103755, ECO:0000269|PubMed:8670811}.
Subcellular Location Nucleus.

DR1 CRISPR/Cas9 KO Plasmid (h) - sc-410764 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DR1 HDR Plasmid (h) - sc-410764-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DR1 Double Nickase Plasmid (h) - sc-410764-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DR1 Double Nickase Plasmid (h2) - sc-410764-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DR1 CRISPR Activation Plasmid (h) - sc-410764-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DR1 CRISPR Activation Plasmid (h2) - sc-410764-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DR1 Lentiviral Activation Particles (h) - sc-410764-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DR1 Lentiviral Activation Particles (h2) - sc-410764-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DR1 siRNA (h) - sc-62238 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DR1 shRNA Plasmid (h) - sc-62238-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DR1 shRNA (h) Lentiviral Particles - sc-62238-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DR1 RNAi - H00001810-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU002811 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7485 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7485 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

DR1 siRNA (Human) - CRH1262 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DR1 - MBS8219304 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DR1 (NM_001938.2) - SHH280945 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human DR1(NM_001938.2) - SHH015455 from Creative biogene

Category siRNA
Species Reactivities Human

Human DR1 siRNA - orb261764 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DR1 shRNA Plasmid (Human) - CHH1262 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DR1 miRNA 3'UTR clone - MiUTR1H-02990 from Creative biogene

Species Reactivities Human
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