DR1

Gene Symbol DR1
Entrez Gene 1810
Alt Symbol NC2, NC2-BETA
Species Human
Gene Type protein-coding
Description down-regulator of transcription 1, TBP-binding (negative cofactor 2)
Other Description TATA-binding protein-associated phosphoprotein|negative cofactor 2-beta|protein Dr1
Swissprots Q01658
Accessions EAW73072 EAW73073 EAW73074 EAW73075 EAW73076 Q01658 AK057541 BAG51931 AK223442 BAD97162 AK311288 AL137673 AL833729 CAH56250 BC002809 AAH02809 BC035507 AAH35507 BC068553 AAH68553 BT006972 AAP35618 M97388 AAA58442 NM_001938 NP_001929
Function The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. {ECO:0000269|PubMed:19103755, ECO:0000269|PubMed:8670811}.
Subcellular Location Nucleus.

DR1 Antibody - 6447 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using DR1 Antibody.

DR1 (A-14) - sc-67620 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

DR1 (FL-176) - sc-367195 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
DR1 (FL-176): sc-367195. Western blot analysis of DR1 expression in HeLa (A), RAW 264.7 (B) and Jurkat (C) whole cell lysates and mouse testis tissue extract (D).

DR1 (I-14) - sc-67621 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

DR1 (K-15) - sc-67622 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DR1 (K-15): sc-67622. Western blot analysis of DR1 expression in Jurkat (A), NIH/3T3 (B), HeLa (C) and K-562 (D) whole cell lysates and mouse testis tissue extract (E).

DR1 (Q-22) - sc-133522 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
DR1 (Q-22): sc-133522. Western blot analysis of human DR1 transfected 293T whole cell lysate.

Anti-DR1 antibody - ab88597 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-DR1 antibody (ab88597) at 1 µg/ml + PC12 cell lysate at 50 µg

Anti-DR1 antibody - ab28185 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DR1 antibody [EPR13122] - ab180164 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13122
All lanes : Anti-DR1 antibody [EPR13122] (ab180164) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : 293T cell lysateLane 3 : Jurkat cell lysateLane 4 : Human testis lysateLysates/proteins at 10 µg per lane.developed using the ECL technique

Anti-DR1 antibody - Azide free - ab37663 from Abcam

Prices $406.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal
Lane 1 : Anti-DR1 antibody - Azide free (ab37663) at 1/2000 dilutionLanes 2 - 3 : Anti-DR1 antibody - Azide free (ab37663) at 1/500 dilutionLane 1 : E coli-derived fusion protein Lane 2 : 293 cell line.Lane 3 : Hela cells line.SecondaryGoat anti-IgY-HRP. at 1/1000 dilution

Anti-DR1 antibody - ChIP Grade - ab50783 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-DR1 antibody - ChIP Grade (ab50783) at 1.25 µg/ml + Transfected 293T Cell Lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 50000

Anti-DR1 / NC2 Antibody (aa83-112, AP) - LS-C256313 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DR1 / NC2 Antibody (aa83-112, APC) - LS-C256312 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DR1 / NC2 Antibody (aa83-112, Azide-free, HRP) - LS-C256316 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DR1 / NC2 Antibody (aa83-112, FITC) - LS-C256315 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DR1 / NC2 Antibody (aa83-112, Biotin) - LS-C256314 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DR1 / NC2 Antibody (aa83-112, PE) - LS-C256317 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DR1 / NC2 Antibody (aa82-112) - LS-C320949 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DR1 / NC2 Antibody (N-Terminus) - LS-C30584 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
A: Marker, B: Transfected 293T Cell Lysate

Anti-DR1 / NC2 Antibody - LS-C307885 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-DR1 / NC2 Antibody (aa63-112) - LS-C145911 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
DR1 antibody LS-C145911 Western blot of Mouse Kidney lysate. Antibody concentration 1 ug/ml.

Anti-DR1 / NC2 Antibody (aa25-75) - LS-C288644 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human DR1 by Western Blot. Samples: Whole cell lysate (5, 15 and 50 ug) from HeLa cells. Antibodies: Affinity purified rabbit anti-DR1 antibody used for WB at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Anti-DR1 / NC2 Antibody (aa2-170) - LS-C314729 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant DR1.

Anti-DR1 / NC2 Antibody (aa83-112) - LS-C159487 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
DR1 Antibody western blot of mouse kidney tissue lysates (35 ug/lane). The DR1 antibody detected the DR1 protein (arrow).

DR1 Antibody - H00001810-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: DR1 Antibody [H00001810-B01] - DR1 MaxPab polyclonal antibody. Western Blot analysis of DR1 expression in Jurkat.
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