NUP153

Gene Symbol	NUP153
Entrez Gene	9972
Alt Symbol	HNUP153, N153
Species	Human
Gene Type	protein-coding
Description	nucleoporin 153kDa
Other Description	153 kDa nucleoporin|nuclear pore complex protein Nup153|nuclear pore complex protein hnup153|nucleoporin 153kD|nucleoporin Nup153
Swissprots	Q4LE47 Q5T9I7 P49790 F6QR24 E7EPX5 B4DIK2 Q7Z743
Accessions	EAW55384 EAW55385 P49790 AB210024 BAE06106 AI948895 AK295644 BAG58514 AL597150 AW269393 BC052965 AAH52965 CB217525 DA856239 Z25535 CAA80982 XM_005249507 XP_005249564 XM_006715290 XP_006715353 XM_006715291 XP_006715354 XM_011515028 XP_011513330 NM_001278209 NP_001265138 NM_001278210 NP_001265139 NM_005124 NP_005115
Function	Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs. Involved in the quality control and retention of unspliced mRNAs in the nucleus; in association with TPR, regulates the nuclear export of unspliced mRNA species bearing constitutive transport element (CTE) in a NXF1- and KHDRBS1-independent manner. Mediates TPR anchoring to the nuclear membrane at NPC. The repeat- containing domain may be involved in anchoring other components of the NPC to the pore membrane. Possible DNA-binding subunit of the nuclear pore complex (NPC). {ECO:0000269|PubMed:12802065, ECO:0000269|PubMed:15229283, ECO:0000269|PubMed:22253824}.
Subcellular Location	Nucleus. Nucleus membrane. Nucleus, nuclear pore complex. Note=Tightly associated with the nuclear membrane and lamina (By similarity). Localized to the nucleoplasmic side of the nuclear pore complex (NPC) core structure, forming a fibrous structure called the nuclear basket. Dissociates from the NPC structure early during prophase of mitosis. Integrated in the newly assembled nuclear envelope of postmitotic cells early in G1. Colocalized with NUP98 and TPR to the nuclear basket at the nucleoplasmic side of the NPC. Detected in diffuse and discrete intranuclear foci. Remained localized to the nuclear membrane after poliovirus (PV) infection. {ECO:0000250}.
Top Pathways	RNA transport

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Nup153 (C-14) - sc-20590 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Nup153 (H-161) - sc-292438 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Nup153 (R3G1) - sc-101544 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rat Clonality Monoclonal

Nup153 (R4C8) - sc-101545 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rat Clonality Monoclonal

Anti-Nup153 antibody - ab84872 from Abcam Prices $388.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-Nup153 antibody [EPR7606(2)(B)] - ab171074 from Abcam Prices $385.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR7606(2)(B)

Anti-Nup153 antibody [nup7A8] - ab93310 from Abcam Prices $373.00 Sizes 2.5 ml Host Mouse Clonality Monoclonal Clone nup7A8

Anti-Nup153 antibody [QE5] - ab24700 from Abcam Prices $391.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone QE5

Anti-Nup153 antibody [QE5] - BSA and Azide free - ab173232 from Abcam Prices $372.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone QE5

Anti-Nup153 antibody [R4C8] - ab81463 from Abcam Prices $384.00 Sizes 200 µg Host Rat Clonality Monoclonal Clone R4C8

Anti-Nup153 antibody - Aminoterminal end - ab95265 from Abcam Prices $359.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-NUP153 Antibody (clone nup7A8) - LS-C85349 from LifeSpan Bioscience Prices $560.00 Sizes 5 ml Host Mouse Clonality Monoclonal Clone nup7A8

Anti-NUP153 Antibody - LS-C9358 from LifeSpan Bioscience Prices $560.00 Sizes 5 ml Host Mouse Clonality Monoclonal

Anti-NUP153 Antibody (aa1425-1475) - LS-C126077 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-NUP153 Antibody (aa50-100) - LS-C126078 from LifeSpan Bioscience Prices $545.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-NUP153 Antibody (aa1066-1081) - LS-C148996 from LifeSpan Bioscience Host Rabbit Clonality Polyclonal

Anti-NUP153 Antibody (aa1456-1475) - LS-C82210 from LifeSpan Bioscience Prices $450.00 Sizes 2 ml Host Sheep Clonality Polyclonal

Anti-NUP153 Antibody (aa21-36) - LS-C148997 from LifeSpan Bioscience Host Rabbit Clonality Polyclonal

Anti-NUP153 Antibody (aa1425-1475) - LS-C288571 from LifeSpan Bioscience Prices $375.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-NUP153 Antibody (aa1127-1176) - LS-C145463 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-NUP153 Antibody (aa1238-1468) - LS-C314706 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-NUP153 Antibody (aa50-100) - LS-C288570 from LifeSpan Bioscience Prices $375.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-NUP153 Antibody (aa58-86) - LS-C163068 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-NUP153 Antibody (aa50-100) - LS-C286603 from LifeSpan Bioscience Prices $415.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Nup153 Antibody - NB100-93329 from Novus Biologicals Prices $359.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

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