NUP153

Gene Symbol	NUP153
Entrez Gene	9972
Alt Symbol	HNUP153, N153
Species	Human
Gene Type	protein-coding
Description	nucleoporin 153kDa
Other Description	153 kDa nucleoporin|nuclear pore complex protein Nup153|nuclear pore complex protein hnup153|nucleoporin 153kD|nucleoporin Nup153
Swissprots	Q4LE47 Q5T9I7 P49790 F6QR24 E7EPX5 B4DIK2 Q7Z743
Accessions	EAW55384 EAW55385 P49790 AB210024 BAE06106 AI948895 AK295644 BAG58514 AL597150 AW269393 BC052965 AAH52965 CB217525 DA856239 Z25535 CAA80982 XM_005249507 XP_005249564 XM_006715290 XP_006715353 XM_006715291 XP_006715354 XM_011515028 XP_011513330 NM_001278209 NP_001265138 NM_001278210 NP_001265139 NM_005124 NP_005115
Function	Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs. Involved in the quality control and retention of unspliced mRNAs in the nucleus; in association with TPR, regulates the nuclear export of unspliced mRNA species bearing constitutive transport element (CTE) in a NXF1- and KHDRBS1-independent manner. Mediates TPR anchoring to the nuclear membrane at NPC. The repeat- containing domain may be involved in anchoring other components of the NPC to the pore membrane. Possible DNA-binding subunit of the nuclear pore complex (NPC). {ECO:0000269|PubMed:12802065, ECO:0000269|PubMed:15229283, ECO:0000269|PubMed:22253824}.
Subcellular Location	Nucleus. Nucleus membrane. Nucleus, nuclear pore complex. Note=Tightly associated with the nuclear membrane and lamina (By similarity). Localized to the nucleoplasmic side of the nuclear pore complex (NPC) core structure, forming a fibrous structure called the nuclear basket. Dissociates from the NPC structure early during prophase of mitosis. Integrated in the newly assembled nuclear envelope of postmitotic cells early in G1. Colocalized with NUP98 and TPR to the nuclear basket at the nucleoplasmic side of the NPC. Detected in diffuse and discrete intranuclear foci. Remained localized to the nuclear membrane after poliovirus (PV) infection. {ECO:0000250}.
Top Pathways	RNA transport

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Nup153 protein fragment - ab153032 from Abcam Category Protein Source Wheat germ Species Human

NUP153 Antibody Blocking Peptide - LS-E22467 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NUP153 Antibody Blocking Peptide - LS-E9946 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NUP153-Antibody-N-term-Blocking-Peptide - BP9116a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human NUP153 protein - orb244415 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

NUP153 - H00009972-Q01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

NUP153 fusion protein - ag5519 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human NUP153, GST-tagged - NUP153-1414H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Nucleoporin 153kDa (NUP153) - RPB147Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Nucleoporin 153kDa (NUP153) - RPB147Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Nuclear pore complex protein Nup153(NUP153) ,partial - CSB-YP016190HU CSB-BP016190HU CSB-MP016190HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant human Nuclear pore complex protein Nup153 - CSB-EP016190HU from Cusabio Category Protein Source E.coli Species Human

Nucleoporin 153kDa Protein (Recombinant) - abx166550 from Abbexa Category Protein Source Human Species Human

Nup153 Recombinant Protein Antigen - NBP1-81725PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Nup153 Recombinant Protein Antigen - NBP1-81724PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Nup153 Recombinant Protein Antigen - NBP1-81723PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NUP153 Peptide, Human - M34GP10732H from Creative Peptides Category Peptide Source Synthetic. Species Human

NUP153 Recombinant Protein (OPCA01763) - OPCA01763 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

Recombinant Nucleoporin 153kDa (NUP153) - RPU51760 from Biomatik Category Protein Prices $180.00, $369.00, $564.00, $672.40 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

NUP153 Recombinant Protein (OPCD05847) - OPCD05847 from Aviva Systems Biology Category Protein Source E.coli Species Human

Recombinant human Nuclear pore complex protein Nup153 - AP70600 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

Nuclear pore complex protein Nup153, Recombinant Protein - MBS949865 from MyBioSource Category Protein Prices $185.00, $420.00, $680.00, $1,070.00 Sizes 50 µg (E-Coli), 200 µg (E-Coli), 500 µg (E-Coli), 1 mg (E-Coli) Source E Coli or Yeast or Baculovirus or Mammalian Cell

Nuclear pore complex protein Nup153, Recombinant Protein - MBS9420506 from MyBioSource Category Protein Prices $280.00, $665.00, $1,080.00, $1,690.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E Coli Species Human

Recombinant Human NUP153 Protein (657-880 aa), His-tagged - NUP153-695H from Creative Biomart Category Protein Source E. coli Species Human

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