SCG5

Gene Symbol	SCG5
Entrez Gene	6447
Alt Symbol	7B2, P7B2, SGNE1, SgV
Species	Human
Gene Type	protein-coding
Description	secretogranin V
Other Description	neuroendocrine protein 7B2|pituitary polypeptide|prohormone convertase chaperone|secretogranin V (7B2 protein)|secretogranin-5|secretory granule endocrine protein I|secretory granule, neuroendocrine protein 1 (7B2 protein)
Swissprots	Q9BS38 Q6FHD0 P01164 P05408
Accessions	CAB90397 EAW92261 EAW92262 EAW92263 P05408 AK314965 BC005349 AAH05349 BC093053 AAH93053 BP377248 CR541824 CAG46623 Y00757 CAA68726 XM_005254595 XP_005254652 XM_005254596 XP_005254653 XM_011548932 XP_011547234 XM_011548933 XP_011547235 NM_001144757 NP_001138229 NM_003020 NP_003011
Function	Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro. {ECO:0000269|PubMed:7913882}.
Subcellular Location	Secreted. Note=Neuroendocrine and endocrine secretory granules.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-SCG5-cDNA-Clone - DC01739 from Abgent, a WuXi AppTec company Prices $286.20 Sizes 10 µg Species Human Accession BC005349

SCG5 - MBS1268745 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC005349

Human SCG5 cDNA clone(NM_001144757.1) - CDFH016971 from Creative Biomart

Human SCG5 ORF Clone(NM_001144757.1) - CDCL174660 from Creative Biomart Species Human Accession NM_001144757.1

Human SCG5 ORF Clone(NM_001144757.1) - CDCR352139 from Creative Biomart Species Human Accession NM_001144757.1

Human SCG5 ORF Clone(NM_001144757.1) - CDCR352140 from Creative Biomart Species Human Accession NM_001144757.1

Human SCG5 Gene ORF cDNA clone in cloning vector - HG13611-G from Sino Biological Species Human

Human SCG5 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13611-CM from Sino Biological Species Human

Human SCG5 Gene ORF cDNA clone expression plasmid, N-His tag - HG13611-NH from Sino Biological Species Human

Human SCG5 Gene ORF cDNA clone expression plasmid, C-HA tag - HG13611-CY from Sino Biological Species Human

Human SCG5 Gene ORF cDNA clone expression plasmid, C-His tag - HG13611-CH from Sino Biological Species Human

Human SCG5 Gene ORF cDNA clone expression plasmid - HG13611-UT from Sino Biological Species Human

Human SCG5 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13611-ACR from Sino Biological Species Human

Human SCG5 Gene ORF cDNA clone expression plasmid, N-HA tag - HG13611-NY from Sino Biological Species Human

Human SCG5 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13611-ACG from Sino Biological Species Human

Human SCG5 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13611-NF from Sino Biological Species Human

Human SCG5 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13611-NM from Sino Biological Species Human

Human SCG5 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13611-CF from Sino Biological Species Human

human SCG5 ORF clone (NM_001144757.1) - CDCH077318 from Creative biogene Species Human

Human SCG5 ORF clone (BC005349) - CDCB159634 from Creative biogene Species Human

Human SCG5 cDNA Clone(NM_001144757.1) - CDFH016971 from Creative biogene Species Human

Human SCG5 ORF Clone (BC005349) - CDCS408399 from Creative biogene Species Human Accession P05408

Human SCG5 Gene cDNA Clone - orb145181 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

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