SCG5

Gene Symbol	SCG5
Entrez Gene	6447
Alt Symbol	7B2, P7B2, SGNE1, SgV
Species	Human
Gene Type	protein-coding
Description	secretogranin V
Other Description	neuroendocrine protein 7B2|pituitary polypeptide|prohormone convertase chaperone|secretogranin V (7B2 protein)|secretogranin-5|secretory granule endocrine protein I|secretory granule, neuroendocrine protein 1 (7B2 protein)
Swissprots	Q9BS38 Q6FHD0 P01164 P05408
Accessions	CAB90397 EAW92261 EAW92262 EAW92263 P05408 AK314965 BC005349 AAH05349 BC093053 AAH93053 BP377248 CR541824 CAG46623 Y00757 CAA68726 XM_005254595 XP_005254652 XM_005254596 XP_005254653 XM_011548932 XP_011547234 XM_011548933 XP_011547235 NM_001144757 NP_001138229 NM_003020 NP_003011
Function	Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro. {ECO:0000269|PubMed:7913882}.
Subcellular Location	Secreted. Note=Neuroendocrine and endocrine secretory granules.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Secretogranin V full length protein - ab100887 from Abcam Category Protein Source E. coli Species Human

SCG5 / 7B2 Antibody Blocking Peptide - LS-E23283 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SCG5 / 7B2 Antibody Blocking Peptide - LS-E23284 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Secretogranin V Recombinant Protein - H00006447-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

Secretogranin V Partial Recombinant Protein - H00006447-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Secretogranin V Protein - NBP1-48343 from Novus Biologicals Category Protein Prices $309.00 Sizes 50 µg Species Human

SCG5 Protein (OPPA00200) - OPPA00200 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source Escherichia Coli.

Human Secretogranin-5 R protein - orb163406 from Biorbyt Category Protein Prices $306.00, $451.00, $1,751.00, $2,474.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Source Human Cells Species Human

Human Secretogranin V protein - orb81351 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg

SCG5 protein (His tag) - 80R-1455 from Fitzgerald Category Protein Prices $255.00 Sizes 50 µg Source E.coli

Secretogranin-5 (SCG5) (27-212, His-tag) - AR09631PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

Secretogranin-5 (SCG5) (27-212, His-tag) - AR09631PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

Secretogranin-5 (SCG5) - H00006447-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

Secretogranin-5 (SCG5) - H00006447-P01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

Secretogranin-5 (SCG5) - H00006447-P01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Species Human

Secretogranin-5 (SCG5) - H00006447-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Secretogranin-5 (SCG5) - H00006447-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SCG5, 27-212aa, Human, His tag, E.coli - 01-1924-5 from ARP American Research Products Category Protein Prices $149.00, $369.00, $849.00 Sizes 10 µg, 50 µg, 250 µg Species Human

SCG5 fusion protein - ag1107 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

SCG5 Human - PRPS-474 from NeoScientific Category Protein Prices $65.00, $169.00, $6,760.00 Sizes 2 µg, 10 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human SCG5 Protein - BP001779-C634 from Syd Labs Category Protein Prices $126.00, $378.00, $2,640.00 Sizes 10 µg, 50 µg, 1 mg Source HEK 293-derived. Species Human

Recombinant Human SCG5 Protein - BP001779-PRO-467 from Syd Labs Category Protein Prices $160.00, $5,200.00 Sizes 10 µg, 1 mg Source E. coli-derived. Species Human

SCG5, 27-212aa, Recombinant Protein - GWB-P1345F from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 50 μg, 250 μg Source E.coli Species Human

Recombinant Human SCG5, His-tagged - SCG5-30595TH from Creative Biomart Category Protein Source E. coli

Recombinant Human Secretogranin V (7B2 Protein), His-tagged - SCG5-2795H from Creative Biomart Category Protein Source E.coli.

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