SCG5

Gene Symbol SCG5
Entrez Gene 6447
Alt Symbol 7B2, P7B2, SGNE1, SgV
Species Human
Gene Type protein-coding
Description secretogranin V
Other Description neuroendocrine protein 7B2|pituitary polypeptide|prohormone convertase chaperone|secretogranin V (7B2 protein)|secretogranin-5|secretory granule endocrine protein I|secretory granule, neuroendocrine protein 1 (7B2 protein)
Swissprots Q9BS38 Q6FHD0 P01164 P05408
Accessions CAB90397 EAW92261 EAW92262 EAW92263 P05408 AK314965 BC005349 AAH05349 BC093053 AAH93053 BP377248 CR541824 CAG46623 Y00757 CAA68726 XM_005254595 XP_005254652 XM_005254596 XP_005254653 XM_011548932 XP_011547234 XM_011548933 XP_011547235 NM_001144757 NP_001138229 NM_003020 NP_003011
Function Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro. {ECO:0000269|PubMed:7913882}.
Subcellular Location Secreted. Note=Neuroendocrine and endocrine secretory granules.

Sg V CRISPR/Cas9 KO Plasmid (h) - sc-408049 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sg V HDR Plasmid (h) - sc-408049-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sg V Double Nickase Plasmid (h) - sc-408049-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sg V Double Nickase Plasmid (h2) - sc-408049-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sg V CRISPR Activation Plasmid (h) - sc-408049-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sg V CRISPR Activation Plasmid (h2) - sc-408049-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sg V Lentiviral Activation Particles (h) - sc-408049-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sg V Lentiviral Activation Particles (h2) - sc-408049-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Sg V siRNA (h) - sc-76489 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Sg V shRNA Plasmid (h) - sc-76489-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Sg V shRNA (h) Lentiviral Particles - sc-76489-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Secretogranin V RNAi - H00006447-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU160261 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN18929 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18929 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04419 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04419

SCG5 siRNA (Human) - CRH4358 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SCG5 - MBS8232519 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SCG5 (NM_003020.3) - SHH402568 from Creative biogene

Category siRNA
Species Reactivities Human

SCG5 shRNA Plasmid (Human) - CHH4358 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SCG5 miRNA 3'UTR clone - MiUTR3H-01754 from Creative biogene

Species Reactivities Human

SCG5 miRNA 3'UTR clone - MiUTR3H-01755 from Creative biogene

Species Reactivities Human
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